LMC Diabetes and Endocrinology, Toronto, Ontario, Canada.
Canadian Heart Research Centre, Toronto, Ontario, Canada; LinCorp Medical Inc, Toronto, Ontario, Canada.
Can J Diabetes. 2022 Jul;46(5):464-472. doi: 10.1016/j.jcjd.2022.01.008. Epub 2022 Feb 3.
Diabetes remains the leading contributor to the development of chronic kidney disease (CKD) and end-stage kidney disease, emphasizing the urgency of identifying barriers to early diagnosis and intervention. The primary objective of this study was to describe the awareness, values and preferences of physicians and patients with respect to managing CKD among patients with type 2 diabetes (T2D).
A cross-sectional survey was conducted among physicians and adult patients with T2D and CKD based on estimated glomerular filtration rate and urine albumin-to-creatinine ratio (uACR) measured within 1 year. Physicians were recruited from email networks across Canada, excluding Alberta, and patients were recruited from LMC Diabetes and Endocrinology clinics in Ontario and Quebec. Two separate surveys were developed by a steering committee. Survey responses from 160 physicians (60 general practitioners, 50 endocrinologists and 50 nephrologists) and 169 patients were analyzed descriptively.
Gaps in physician care included insufficient use of uACR screening, limited knowledge or use of Kidney Disease Improving Global Outcomes (KDIGO) and KidneyWise resources and lower than expected prescription of recommended therapies. The patient data showed 51.5% of patients were unaware of a CKD diagnosis, and 75.6% of patients who received a prior CKD diagnosis would have preferred an earlier diagnosis.
The results highlight several opportunities for improving CKD in T2D management. More education and clarity are needed for physicians interpreting uACR levels that should prompt a referral to a nephrologist, and additional understanding of kidney risk progression is vital for patients.
糖尿病仍然是导致慢性肾脏病(CKD)和终末期肾病的主要原因,这强调了迫切需要确定早期诊断和干预的障碍。本研究的主要目的是描述 2 型糖尿病(T2D)患者中管理 CKD 的医生和患者的意识、价值观和偏好。
根据在 1 年内测量的估计肾小球滤过率和尿白蛋白与肌酐比(uACR),对加拿大各地的医生和 T2D 及 CKD 成年患者进行了横断面调查,但艾伯塔省除外。医生是从电子邮件网络招募的,而患者是从安大略省和魁北克省的 LMC 糖尿病和内分泌诊所招募的。一个指导委员会制定了两个单独的调查。对 160 名医生(60 名全科医生、50 名内分泌学家和 50 名肾病学家)和 169 名患者的调查回复进行了描述性分析。
医生护理方面的差距包括 uACR 筛查使用不足、对肾脏病改善全球结局(KDIGO)和 KidneyWise 资源的了解或使用有限以及推荐疗法的处方低于预期。患者数据显示,51.5%的患者不知道 CKD 诊断,75.6%的曾接受过 CKD 诊断的患者希望更早得到诊断。
结果突出了改善 T2D 管理中 CKD 的几个机会。需要对解释 uACR 水平的医生进行更多的教育和澄清,以促使他们转介给肾病学家,并且患者还需要进一步了解肾脏风险进展。