Suppr超能文献

关注肾脏护理的差距:将我们所知转化为我们所行。

Mind the gap in kidney care: Translating what we know into what we do.

作者信息

Luyckx Valerie A, Tuttle Katherine R, Abdellatif Dina, Correa-Rotter Ricardo, Fung Winston W S, Haris Agnès, Hsiao Li-Li, Khalife Makram, Kumaraswami Latha A, Loud Fiona, Raghavan Vasundhara, Roumeliotis Stefanos, Sierra Marianella, Ulasi Ifeoma, Wang Bill, Lui Siu-Fai, Liakopoulos Vassilios, Balducci Alessandro

机构信息

Department of Public and Global Health, Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.

Renal Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

出版信息

Nephrology (Carlton). 2025 Jan;30(1):e14314. doi: 10.1111/nep.14314.

Abstract

Historically, it takes an average of 17 years to move new treatments from clinical evidence to daily practice. Given the highly effective treatments now available to prevent or delay kidney disease onset and progression, this is far too long. The time is now to narrow the gap between what we know and what we do. Clear guidelines exist for the prevention and management of common risk factors for kidney disease, such as hypertension and diabetes, but only a fraction of people with these conditions worldwide are diagnosed, and even fewer are treated to target. Similarly, the vast majority of people living with kidney disease are unaware of their condition, because in the early stages it is often silent. Even among patients who have been diagnosed, many do not receive appropriate treatment for kidney disease. Considering the serious consequences of kidney disease progression, kidney failure or death, it is imperative that treatments are initiated early and appropriately. Opportunities to diagnose and treat kidney disease early must be maximized beginning at the primary care level. Many systematic barriers exist, ranging from patient to clinician to health systems to societal factors. To preserve and improve kidney health for everyone everywhere, each of these barriers must be acknowledged so that sustainable solutions are developed and implemented without further delay.

摘要

从历史上看,新疗法从临床证据转化为日常实践平均需要17年时间。鉴于目前已有高效疗法可预防或延缓肾脏疾病的发生和发展,这个时间实在太长了。现在是时候缩小我们所知与所为之间的差距了。对于肾脏疾病常见风险因素(如高血压和糖尿病)的预防和管理,已有明确的指南,但全球范围内只有一小部分患有这些疾病的人得到诊断,接受治疗并达到目标的人更少。同样,绝大多数肾病患者并不知道自己的病情,因为在疾病早期往往没有症状。即使在已被诊断的患者中,许多人也没有接受针对肾脏疾病的适当治疗。考虑到肾病进展、肾衰竭或死亡的严重后果,必须尽早并适当地开始治疗。必须从初级保健层面开始,最大限度地利用早期诊断和治疗肾脏疾病的机会。存在许多系统性障碍,从患者到临床医生,再到卫生系统和社会因素。为了在世界各地为每个人维护和改善肾脏健康,必须认识到每一个障碍,以便立即制定和实施可持续的解决方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/959b/11718150/17ea541804b7/NEP-30-0-g004.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验