Hsu Chen-Heng, Hu Chih-Chien, Chang Chih-Hsiang, Chang Yu-Han, Shih Hsin-Nung, Chen Chun-Chieh
Department of Orthopedic Surgery, Chang Gung Memorial Hospital, Taoyuan 333423, Taiwan.
Bone and Joint Research Center, Chang Gung Memorial Hospital, Taoyuan 33305, Taiwan.
J Clin Med. 2022 Jun 15;11(12):3428. doi: 10.3390/jcm11123428.
Background: Acetabular cage reconstruction with bone allografts is among the successful strategies to deal with massive acetabular bone loss. However, the nonbiological fixation nature of cages can compromise long-term success. Tantalum trabecular metal acetabular cups (TM cups) have been used in acetabular revision surgery because of their increased initial stability and good bone ingrowth features. This study was performed to determine whether the bone stock of the acetabulum is enough to support a hemispheric TM cup after failed cage reconstruction with bone allografts. Methods: We retrospectively reviewed patients who received acetabular revision surgery with TM cups after failed cage reconstruction with bone allografts from 2006 to 2017. There were 12 patients (5 males and 7 females) included in this study, with a mean age of 61.5 years (38 to 81) at the time of re-revision surgery. The mean follow-up after re-revision surgery was 8.6 years (2.6 to 13.3). The endpoint was defined as the aseptic loosening of the TM cup and reoperation for any causes. The change in bone stock of the acetabulum between index revision and re-revision was assessed according to the Gross classification for acetabular bone loss. Results: One patient died after eight years of follow-up of a cause not related to hip surgery. Two patients received two-stage revision arthroplasty due to PJI after 3.2 and 9.4 years of follow-up, respectively. The bone stock of the acetabulum was significantly improved between index revision and re-revision surgery (p < 0.0001). The Kaplan−Meier survivorship was 100% with aseptic loosening as the endpoint and 90% and 75% at five- and ten-year follow-up, respectively, with reoperation for any reason as the endpoint. Even cage reconstruction with bone allografts will fail eventually, and the bone stock of the acetabulum will improve after union and incorporation between host bone and allografts. The restored bone stocks will facilitate further revision surgery with hemispheric TM cups. The biological fixation between host bone and tantalum trabecular metal can provide longstanding stability of the TM cup. Conclusions: The results of our study offer a viable option for patients with failed cage reconstruction with bone allografts.
采用同种异体骨进行髋臼笼重建是应对髋臼大量骨缺损的成功策略之一。然而,髋臼笼的非生物固定特性可能会影响长期疗效。钽小梁金属髋臼杯(TM杯)因其初始稳定性增加和良好的骨长入特性,已被用于髋臼翻修手术。本研究旨在确定在同种异体骨笼重建失败后,髋臼的骨量是否足以支撑半球形TM杯。方法:我们回顾性分析了2006年至2017年间接受同种异体骨笼重建失败后行TM杯髋臼翻修手术的患者。本研究共纳入12例患者(5例男性,7例女性),再次翻修手术时的平均年龄为61.5岁(38至81岁)。再次翻修手术后的平均随访时间为8.6年(2.6至13.3年)。终点定义为TM杯无菌性松动及因任何原因进行再次手术。根据髋臼骨缺损的Gross分类评估初次翻修和再次翻修之间髋臼骨量的变化。结果:1例患者在随访8年后因与髋关节手术无关的原因死亡。2例患者分别在随访3.2年和9.4年后因假体周围感染性关节炎接受二期翻修关节成形术。初次翻修和再次翻修手术之间髋臼的骨量有显著改善(p < 0.0001)。以无菌性松动为终点的Kaplan-Meier生存率为100%,以因任何原因再次手术为终点的5年和10年随访生存率分别为90%和75%。即使同种异体骨笼重建最终会失败,但在宿主骨与同种异体骨联合并融合后,髋臼的骨量会改善。恢复的骨量将有助于使用半球形TM杯进行进一步的翻修手术。宿主骨与钽小梁金属之间的生物固定可提供TM杯的长期稳定性。结论:我们的研究结果为同种异体骨笼重建失败的患者提供了一个可行的选择。