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小儿脊柱裂与脊髓损伤

Pediatric Spina Bifida and Spinal Cord Injury.

作者信息

Gober Joslyn, Thomas Sruthi P, Gater David R

机构信息

Department of Physical Medicine and Rehabilitation, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.

The Christine E. Lynn Rehabilitation Center for the Miami Project to Cure Paralysis, Miami, FL 33136, USA.

出版信息

J Pers Med. 2022 Jun 17;12(6):985. doi: 10.3390/jpm12060985.

DOI:10.3390/jpm12060985
PMID:35743769
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9225638/
Abstract

Pediatric spina bifida (SB) and spinal cord injury (SCI) are unfortunately common in our society, and their unique findings and comorbidities warrant special consideration. This manuscript will discuss the epidemiology, pathophysiology, prevention, and management strategies for children growing and developing with these unique neuromuscular disorders. Growth and development of the maturing child places them at high risk of spinal cord tethering, syringomyelia, ascending paralysis, pressure injuries, and orthopedic abnormalities that must be addressed frequently and judiciously. Similarly, proper neurogenic bladder and neurogenic bowel management is essential not just for medical safety, but also for optimal psychosocial integration into the child's expanding social circle.

摘要

不幸的是,小儿脊柱裂(SB)和脊髓损伤(SCI)在我们的社会中很常见,其独特的表现和合并症值得特别关注。本文将讨论患有这些独特神经肌肉疾病的儿童在生长发育过程中的流行病学、病理生理学、预防和管理策略。成熟儿童的生长发育使他们面临脊髓栓系、脊髓空洞症、上行性麻痹、压力性损伤和骨科异常的高风险,必须经常且谨慎地加以处理。同样,正确的神经源性膀胱和神经源性肠道管理不仅对医疗安全至关重要,而且对于儿童融入不断扩大的社交圈以实现最佳心理社会整合也至关重要。

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本文引用的文献

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Neural tube defects: Different types and brief review of neurulation process and its clinical implication.神经管缺陷:不同类型以及神经胚形成过程及其临床意义的简要综述。
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Characteristics and first-year mortality, by lesion level, among infants with spina bifida in the New York State Birth Defects Registry, 2008-2017.2008 - 2017年纽约州出生缺陷登记处中脊柱裂婴儿按病变水平划分的特征及首年死亡率
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