Mazzucchi Edoardo, La Rocca Giuseppe, Perna Andrea, Pignotti Fabrizio, Galieri Gianluca, De Santis Vincenzo, Rinaldi Pierluigi, Tamburrelli Francesco Ciro, Sabatino Giovanni
Department of Neurosurgery, Mater Olbia Hospital, 07026 Olbia, Italy.
Institute of Neurosurgery, IRCCS Fondazione Policlinico Universitario Agostino Gemelli, Catholic University, 00168 Rome, Italy.
J Pers Med. 2022 Jun 17;12(6):986. doi: 10.3390/jpm12060986.
Background: Anterior cervical discectomy and interbody fusion (ACDF) may be performed with different kinds of stand-alone cages. Tantalum and polyetheretherketone (PEEK) are two of the most commonly used materials in this procedure. Few comparisons between different stand-alone implants for ACDF have been reported in the literature. Methods: We performed a comparison between patients who underwent ACDF with either a porous tantalum or a PEEK stand-alone cage, in two spine surgery units for single-level disc herniation. Clinical outcome [Neck Disability Index (NDI), Visual Analog Scale (VAS) for pain, Short Form-36 (SF-36)] and radiological outcome (lordosis, fusion and subsidence) were measured before surgery and at least one year after surgery in both groups. Results: Thirty-eight patients underwent ACDF with a porous tantalum cage, and thirty-one with a PEEK cage. The improvement of NDI and SF-36 was significantly superior in the PEEK group (p = 0.002 and p = 0.049 respectively). Moreover, the variation of the Cobb angle for the cervical spine was significantly higher in the PEEK group (p < 0.001). Conclusions: In a retrospective analysis of two groups of patients with at least one year of follow-up, a stand-alone PEEK cage showed superior clinical results, with improved cervical lordosis, compared to a stand-alone porous tantalum cage. Further studies are needed to confirm these data.
颈椎前路椎间盘切除融合术（ACDF）可使用不同类型的独立椎间融合器进行。钽和聚醚醚酮（PEEK）是该手术中最常用的两种材料。文献中很少有关于ACDF不同独立植入物之间比较的报道。方法：我们在两个脊柱外科单元对因单节段椎间盘突出症接受ACDF手术的患者进行了比较，一组使用多孔钽独立椎间融合器，另一组使用PEEK独立椎间融合器。在两组患者术前及术后至少一年测量临床结果[颈部功能障碍指数（NDI）、视觉模拟疼痛评分（VAS）、简明健康状况调查量表（SF-36）]和影像学结果（颈椎前凸、融合及下沉情况）。结果：38例患者接受了多孔钽椎间融合器的ACDF手术，31例接受了PEEK椎间融合器的手术。PEEK组NDI和SF-36的改善情况明显更优（分别为p = 0.002和p = 0.049）。此外，PEEK组颈椎Cobb角的变化明显更大（p < 0.001）。结论：在对两组至少随访一年的患者进行的回顾性分析中，与多孔钽独立椎间融合器相比，PEEK独立椎间融合器显示出更优的临床结果，颈椎前凸得到改善。需要进一步研究来证实这些数据。
