Duarte Tayse Tâmara Paixão, Magro Marcia Cristina Silva
Nursing Department, College of Ceilândia, University of Brasília, Brasília 70910-900, Brazil.
Life (Basel). 2022 Jun 8;12(6):852. doi: 10.3390/life12060852.
To assess the different renal function recovery patterns and their impact on the mortality of non-critical patients with hospital-acquired Acute Kidney Injury.
A prospective cohort study was conducted from January 2017 to December 2019.
The patients included were those with Acute Kidney Injury acquired during their hospitalization, identified from Kidney Disease: Improving Global Outcomes (KDIGO). Renal function recovery was calculated through the serum creatinine ratio in relation to baseline creatinine at the renal function evaluation moment. A descriptive analysis of the results was performed, and the Backward method was adopted for the multivariate analysis.
One-thousand five-hundred and forty-six patients were evaluated in the medical clinic and 202 (13.06%) were identified to have Acute Kidney Injury; among them, renal function recovery varied over the six months of follow-up with greater expressiveness in the second and third months (from 61.02% to 62.79%). Recovery was a protective factor against in-hospital death in the first (OR 0.24; 95% CI 0.09-0.61; -value = 0.038) and sixth month of follow-up (OR 0.24; 95% CI 0.09-0.61; -value = 0.003).
The incidence of renal function recovery varied throughout the six months of follow-up and reached progressively high levels from the second to the third months. Renal recovery was a protective factor against mortality during the follow-up period.
评估非重症医院获得性急性肾损伤患者不同的肾功能恢复模式及其对死亡率的影响。
2017年1月至2019年12月进行了一项前瞻性队列研究。
纳入的患者为住院期间获得急性肾损伤的患者，根据改善全球肾脏病预后组织（KDIGO）标准确定。通过在肾功能评估时血清肌酐与基线肌酐的比值计算肾功能恢复情况。对结果进行描述性分析，并采用向后法进行多变量分析。
在门诊评估了1546例患者，其中202例（13.06%）被确定患有急性肾损伤；在6个月的随访中，肾功能恢复情况有所不同，在第二个月和第三个月表现更为明显（从61.02%至62.79%）。在随访的第一个月（OR 0.24；95%CI 0.09 - 0.61；P值 = 0.038）和第六个月（OR 0.24；95%CI 0.09 - 0.61；P值 = 0.003），恢复是住院死亡的保护因素。
在6个月的随访中，肾功能恢复的发生率各不相同，从第二个月到第三个月逐渐达到较高水平。肾功能恢复是随访期间死亡率的保护因素。
