Karlen J, Stula D
Neurochirurgia (Stuttg). 1987 Mar;30(2):35-9. doi: 10.1055/s-2008-1053653.
During the period from September 1983 to October 1984 the intracranial pressure of 51 patients who had suffered cranio-cerebral trauma was continuously recorded. In 21 patients (41%) the intracranial pressure remained within normal limits (10-25 mm Hg) and apart from hyperventilation and corticosteroids no other treatment was required. All these patients recovered satisfactorily. In 28 patients the raised intracranial pressure could not be reduced by means of hyperventilation, corticosteroids and osmotherapy so that barbiturates had to be administered. Seven patients did not respond to this additional treatment and a decompression craniotomy was necessary. The progress, treatment, complications and prognosis of such patients are discussed.
在1983年9月至1984年10月期间，对51例颅脑外伤患者的颅内压进行了连续记录。21例患者（41%）的颅内压保持在正常范围内（10 - 25毫米汞柱），除了过度换气和使用皮质类固醇外，无需其他治疗。所有这些患者均恢复良好。28例患者的颅内压升高无法通过过度换气、皮质类固醇和渗透性疗法降低，因此必须使用巴比妥类药物。7例患者对这种额外治疗无反应，有必要进行颅骨减压术。文中讨论了此类患者的病情进展、治疗、并发症及预后。
