3D 打印正畸矫治器材料的后冲洗处理程序:替代后冲洗溶液对粗糙度、弯曲强度和细胞毒性的影响。

Rinsing postprocessing procedure of a 3D-printed orthodontic appliance material: Impact of alternative post-rinsing solutions on the roughness, flexural strength and cytotoxicity.

机构信息

Department of Orthodontics, University Hospital Tübingen, Osianderstrasse 2-8, Tübingen 72076, Germany; Medical Materials Science and Technology, University Hospital Tübingen, Osianderstrasse 2-8, Tübingen 72076, Germany.

Department of Orthodontics, University Hospital Tübingen, Osianderstrasse 2-8, Tübingen 72076, Germany.

出版信息

Dent Mater. 2022 Aug;38(8):1344-1353. doi: 10.1016/j.dental.2022.06.010. Epub 2022 Jun 22.

Abstract

OBJECTIVE

The present study evaluated the effect of different rinsing postprocessing solutions on surface characteristics, flexural strength, and cytotoxicity of an additive manufactured polymer for orthodontic appliances. These solutions have been deemed an alternative to the standard isopropanol which is a flammable liquid, known to have toxic effects.

METHODS

Tested specimens were manufactured using direct light processing of an orthodontic appliance polymer (FREEPRINT® splint 2.0, Detax) and post-processed with different post-rinsing solutions, including isopropanol (IPA), ethanol (EtOH), EASY 3D Cleaner (EYC), Yellow Magic7 (YM7), and RESINAWAY (RAY), respectively. All groups were post-cured following the manufacturer's instructions. Surface topography and roughness (Ra and Rv) were evaluated. In addition, flexural strength was measured by a three-point bending test. An extract test was performed to evaluate cytotoxicity. The data were analyzed by the Kruskal-Wallis test with Dunn's multiple comparisons test (p < 0.05).

RESULTS

Various post-rinsing solutions did not significantly affect the roughness values (Ra and Rv). Specimens post-processed with EtOH (98.1 ± 12.4 MPa) and EYC (101.1 ± 6.3 MPa) exhibited significantly lower flexural strength compared to the groups of IPA (110.7 ± 5.3 MPa), RAY (112.1 ± 5.6 MPa) and YM7 (117.3 ± 5.9 MPa), respectively. Finally, there were no cytotoxic effects of parts cleaned with different post-rinsing solutions.

SIGNIFICANCE

Considering the use of 3D-printed orthodontic appliance materials, different rinsing postprocessing procedures did not affect surface characteristics. However, the flexural strength was significantly influenced, which could be attributed to the chemical ingredients of the post-rinsing solutions. Various post-rinsing treatments had no alternation concerning cytocompatibility.

摘要

目的

本研究评估了不同冲洗后处理溶液对正畸矫治器用增材制造聚合物表面特性、弯曲强度和细胞毒性的影响。这些溶液被认为是替代标准异丙醇的一种选择,异丙醇是一种易燃液体,已知具有毒性作用。

方法

使用正畸矫治器聚合物的直接光处理(Detax 的 FREEPRINT® splint 2.0)制造测试样本,并使用不同的后冲洗溶液进行后处理,包括异丙醇(IPA)、乙醇(EtOH)、EASY 3D Cleaner(EYC)、Yellow Magic7(YM7)和 RESINAWAY(RAY)。所有组均按照制造商的说明进行后固化。评估表面形貌和粗糙度(Ra 和 Rv)。此外,通过三点弯曲试验测量弯曲强度。进行提取试验以评估细胞毒性。数据通过 Kruskal-Wallis 检验和 Dunn 多重比较检验(p<0.05)进行分析。

结果

各种后冲洗溶液对粗糙度值(Ra 和 Rv)没有显著影响。用 EtOH(98.1±12.4 MPa)和 EYC(101.1±6.3 MPa)后处理的标本与 IPA(110.7±5.3 MPa)、RAY(112.1±5.6 MPa)和 YM7(117.3±5.9 MPa)组相比,弯曲强度显著降低。最后,用不同后冲洗溶液清洗的部件没有细胞毒性作用。

意义

考虑到 3D 打印正畸矫治器材料的使用,不同的冲洗后处理程序不会影响表面特性。然而,弯曲强度受到显著影响,这可能归因于后冲洗溶液的化学成分。各种后冲洗处理在细胞相容性方面没有变化。

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