后固化条件对3D打印义齿基托聚合物的表面特性、物理机械性能及细胞毒性的影响

Effect of post-curing conditions on surface characteristics, physico-mechanical properties, and cytotoxicity of a 3D-printed denture base polymer.

作者信息

Luo Ke, Liu Qian, Alhotan Abdulaziz, Dai Jingtao, Li An, Xu Shulan, Li Ping

机构信息

Center of Oral Implantology, Stomatological Hospital, School of Stomatology, Southern Medical University, South Jiangnan Road No. 366, Guangzhou 510280, China.

Dental Health Department, College of Applied Medical Sciences, King Saud University, P.O.Box 10219, Riyadh 12372, Saudi Arabia.

出版信息

Dent Mater. 2024 Mar;40(3):500-507. doi: 10.1016/j.dental.2023.12.017. Epub 2024 Jan 5.

Abstract

OBJECTIVE

This study aims to investigate the influence of post-polymerization (post-curing) conditions on surface characteristics, flexural properties, water sorption and solubility, and cytotoxicity of additively manufactured denture base materials.

METHODS

The tested specimens were additively manufactured using digital light processing and classified into different post-curing condition groups: submerged in water (WAT), submerged in glycerin (GLY), and air exposure (AIR). An uncured specimen (UNC) was used as a control. The surface topography and roughness were observed. The flexural strength and modulus were determined via a three-point bending test. The water sorption and solubility were subsequently tested. Finally, an extract test was performed to assess cytotoxicity.

RESULTS

Different post-curing conditions had no significant effects on the surface topography and roughness (Sa value). Various post-curing conditions also had no significant effects on the flexural strength. Notably, the flexural modulus of the WAT group (2671.80 ± 139.42 MPa) was significantly higher than the AIR group (2197.47 ± 197.93 MPa, p = 0.0103). After different post-curing conditions, the water sorption and solubility of the specimens met the ISO standards. Finally, all post-curing conditions effectively reduced cytotoxic effects.

SIGNIFICANCES

Post-curing with different oxygen levels improved flexural properties, and flexural modulus significantly increased after the specimens were submerged in water. In addition, water sorption and solubility, and cytocompatibility were optimized by post-curing, irrespective of the post-curing conditions. Therefore, the water-submerged conditions optimized the flexural modulus of the 3D-printed denture base materials.

摘要

目的

本研究旨在探讨聚合后(后固化)条件对增材制造义齿基托材料的表面特性、弯曲性能、吸水性和溶解性以及细胞毒性的影响。

方法

使用数字光处理技术增材制造测试样本,并将其分为不同的后固化条件组:浸泡在水中(WAT)、浸泡在甘油中(GLY)和空气暴露(AIR)。未固化的样本(UNC)用作对照。观察表面形貌和粗糙度。通过三点弯曲试验测定弯曲强度和模量。随后测试吸水性和溶解性。最后,进行浸提试验以评估细胞毒性。

结果

不同的后固化条件对表面形貌和粗糙度(Sa值)没有显著影响。各种后固化条件对弯曲强度也没有显著影响。值得注意的是,WAT组的弯曲模量(2671.80±139.42MPa)显著高于AIR组(2197.47±197.93MPa,p = 0.0103)。在不同的后固化条件下,样本的吸水性和溶解性符合ISO标准。最后,所有后固化条件均有效降低了细胞毒性作用。

意义

不同氧水平的后固化改善了弯曲性能,样本浸泡在水中后弯曲模量显著增加。此外,无论后固化条件如何,后固化均可优化吸水性和溶解性以及细胞相容性。因此,水浸条件优化了3D打印义齿基托材料的弯曲模量。

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