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叙利亚仓鼠松果体对异丙肾上腺素敏感性的夜间增加依赖于黑暗。

Nocturnal increase in the sensitivity of the Syrian hamster pineal gland to isoproterenol is darkness dependent.

作者信息

Reiter R J, Puig-Domingo M, Guerrero J M, Gonzalez-Brito A

出版信息

Proc Soc Exp Biol Med. 1987 Jun;185(2):219-22. doi: 10.3181/00379727-185-42538.

DOI:10.3181/00379727-185-42538
PMID:3575335
Abstract

The sensitivity of the Syrian hamster pineal gland to stimulation by isoproterenol is greatly increased in the latter half of the daily dark phase. This increased sensitivity requires a period of dark exposure for up to 6.5 hr. Also, if dark-maintained hamsters are exposed to light in the latter half of the night pineal melatonin levels drop precipitously but can be restimulated by isoproterenol administration. As the interval of light exposure continues, however, the pineal sensitivity to isoproterenol decreases.

摘要

叙利亚仓鼠松果体对异丙肾上腺素刺激的敏感性在每日黑暗期的后半段会大幅增加。这种敏感性增加需要长达6.5小时的黑暗暴露期。此外,如果在夜间后半段将处于黑暗环境中的仓鼠暴露于光照下,松果体褪黑素水平会急剧下降,但可通过给予异丙肾上腺素再次刺激。然而,随着光照暴露时间的持续,松果体对异丙肾上腺素的敏感性会降低。

相似文献

1
Nocturnal increase in the sensitivity of the Syrian hamster pineal gland to isoproterenol is darkness dependent.叙利亚仓鼠松果体对异丙肾上腺素敏感性的夜间增加依赖于黑暗。
Proc Soc Exp Biol Med. 1987 Jun;185(2):219-22. doi: 10.3181/00379727-185-42538.
2
Norepinephrine or isoproterenol stimulation of pineal N-acetyltransferase activity and melatonin content in the Syrian hamster is restricted to the second half of the daily dark phase.去甲肾上腺素或异丙肾上腺素对叙利亚仓鼠松果体N-乙酰转移酶活性和褪黑素含量的刺激仅限于每日黑暗期的后半段。
Neuroendocrinology. 1987 Apr;45(4):249-56. doi: 10.1159/000124736.
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mRNA transcription determines the lag period for the induction of pineal melatonin synthesis in the Syrian hamster pineal gland.信使核糖核酸转录决定了叙利亚仓鼠松果体中松果体褪黑素合成诱导的延迟期。
J Cell Biochem. 1990 Sep;44(1):55-60. doi: 10.1002/jcb.240440105.
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Beta-adrenergic stimulation prior to darkness advances the nocturnal increase of Syrian hamster pineal melatonin synthesis.在黑暗来临之前进行β-肾上腺素能刺激可提前叙利亚仓鼠松果体褪黑素合成的夜间增加。
Brain Res. 1988 Dec 20;475(2):393-6. doi: 10.1016/0006-8993(88)90633-6.
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The Syrian hamster pineal gland responds to isoproterenol in vivo at night.叙利亚仓鼠的松果体在夜间对体内的异丙肾上腺素产生反应。
Endocrinology. 1987 Apr;120(4):1682-4. doi: 10.1210/endo-120-4-1682.
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Nyctohemeral rhythm in melatonin response to isoproterenol in vitro: comparison of rats and Syrian hamsters.褪黑素对异丙肾上腺素体外反应的昼夜节律:大鼠和叙利亚仓鼠的比较。
Comp Biochem Physiol C Comp Pharmacol Toxicol. 1987;87(1):71-4. doi: 10.1016/0742-8413(87)90183-6.
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In vivo responses of the pineal gland of the Syrian hamster to isoproterenol or norepinephrine.
Prog Clin Biol Res. 1982;92:107-15.
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Stimulatory effect of isoproterenol but not of dibutyryl cyclic AMP on N-acetyltransferase activity and melatonin content of Syrian hamster pineal gland in organ culture.异丙肾上腺素而非二丁酰环磷腺苷对器官培养的叙利亚仓鼠松果体N-乙酰转移酶活性和褪黑素含量的刺激作用。
Neuroendocrinology. 1988 Sep;48(3):229-34. doi: 10.1159/000125016.
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Comparison of the effects of beta-adrenergic agents on pineal serotonin N-acetyltransferase activity and melatonin content in two species of hamsters.β-肾上腺素能药物对两种仓鼠松果体血清素N-乙酰基转移酶活性和褪黑素含量影响的比较
J Pineal Res. 1984;1(1):23-30. doi: 10.1111/j.1600-079x.1984.tb00192.x.
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In vivo administration of isoproterenol or forskolin during the light phase induces increases in the melatonin content of the Syrian hamster pineal gland without a rise in N-acetyltransferase activity.在光照阶段对叙利亚仓鼠体内注射异丙肾上腺素或福斯高林,可使松果体褪黑素含量增加,而N-乙酰转移酶活性并未升高。
Neurosci Lett. 1990 Mar 14;110(3):314-8. doi: 10.1016/0304-3940(90)90866-8.

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