Diatewa B M, Maneh N, Domingo A S, Amouzou D, Gnansa K, Bawerima W, Ayikoue Y F, Mewamba Wamba R
Service d'ophtalmologie, CHU - Campus de Lomé, Lomé, Togo.
Service d'ophtalmologie, CHU - Campus de Lomé, Lomé, Togo; Faculté des sciences de la santé, université de Lomé, Lomé, Togo.
J Fr Ophtalmol. 2022 Sep;45(7):762-766. doi: 10.1016/j.jfo.2021.08.014. Epub 2022 Jun 23.
Retinoblastoma is a curable cancer when management is early and prompt.
To describe the epidemiological, clinical and therapeutic aspects of retinoblastoma.
A retrospective study was carried out from January 2014 to December 2018 (5 years) at the department of ophthalmology in Campus-University Teaching Hospital, Lomé, Togo. It focused on children with retinoblastoma. It included patients with diagnosis supported by ocular ultrasonography, orbito-cerebral computed tomography scan and/or histopathological examination.
Among the 75 children with ocular cancer, 26 (34.7%) were diagnosed with retinoblastoma. The mean age at presentation was 31 months. The mean time from symptom onset to diagnosis was 15 months. A predominance of proptosis (65.4%), unilateral involvement (76.9%), extraocular tumor extension (65.4%) and endophytic form (96.15%) was found. Of the 32 eyes with retinoblastoma, 7 (21.9%) were enucleated after a mean time from diagnosis to enucleation of 6 months. Two cases of complete remission, 3 cases of tumor recurrence, and 2 cases lost to follow-up were noted.
In our setting, retinoblastoma is a frequent childhood ocular cancer. It is important to improve the management of retinoblastoma as well as education of the parents.
视网膜母细胞瘤若能早期且及时治疗，是一种可治愈的癌症。
描述视网膜母细胞瘤的流行病学、临床及治疗方面的情况。
于2014年1月至2018年12月（5年）在多哥洛美大学教学医院校区眼科进行了一项回顾性研究。研究聚焦于患有视网膜母细胞瘤的儿童。纳入了经眼部超声、眼眶-脑部计算机断层扫描和/或组织病理学检查确诊的患者。
在75例眼部癌症患儿中，26例（34.7%）被诊断为视网膜母细胞瘤。就诊时的平均年龄为31个月。从症状出现到诊断的平均时间为15个月。发现以眼球突出（65.4%）、单侧受累（76.9%）、眼外肿瘤扩展（65.4%）和内生型（96.15%）为主。在32只患有视网膜母细胞瘤的眼睛中，7只（21.9%）在诊断至眼球摘除的平均时间为6个月后被摘除。记录到2例完全缓解、3例肿瘤复发和2例失访。
在我们的研究环境中，视网膜母细胞瘤是一种常见的儿童眼部癌症。改善视网膜母细胞瘤的管理以及对家长的教育很重要。
