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COVID-19 大流行期间医院资源的重新配置及其对资源有限环境下创伤结局的影响。

Reallocation of Hospital Resources During COVID-19 Pandemic and Effect on Trauma Outcomes in a Resource-Limited Setting.

机构信息

Department of Surgery, University of North Carolina School of Medicine, 4006 Burnett Womack Building, Chapel Hill, NC, 27599-7228, USA.

Department of Surgery, Kamuzu Central Hospital, Lilongwe, Malawi.

出版信息

World J Surg. 2022 Sep;46(9):2036-2044. doi: 10.1007/s00268-022-06636-4. Epub 2022 Jun 26.

Abstract

BACKGROUND

The COVID-19 pandemic has caused unprecedented disruptions to surgical care worldwide, particularly in low-resource countries. We sought to characterize the association between pre-and intra-pandemic trauma clinical outcomes at a busy tertiary hospital in Malawi.

METHODS

We analyzed trauma patients that presented to Kamuzu Central Hospital in Lilongwe, Malawi, from 2011 through July 2021. Burn patients were excluded. We compared patients based on whether they presented before or during the pandemic (defined as starting March 11, 2020, the date of the official WHO designation). We used logistic regression modeling to estimate the adjusted odds ratio of death based on presentation.

RESULTS

A total of 137,867 patients presented during the study period, with 13,526 patients during the pandemic. During the pandemic, patients were more likely to be older (mean 28 vs. 25 years, p < 0.001), male (79 vs. 74%, p < 0.001), and suffer a traumatic brain injury (TBI) as their primary injury (9.7 vs. 4.9%, p < 0.001). Crude trauma-associated mortality was higher during the pandemic at 3.7% vs. 2.1% (p < 0.001). The odds ratio of mortality during the pandemic compared to pre-pandemic presentation was 1.28 (95% CI 1.06, 1.53) adjusted for age, sex, initial AVPU score, transfer status, injury type, and mechanism.

CONCLUSIONS

During the pandemic, adjusted trauma-associated mortality significantly increased at a tertiary trauma center in a low-resource setting despite decreasing patient volume. Further research is urgently needed to prepare for future pandemics. Potential targets for improvement include improving pre-hospital care and transportation, planning for intensive care utilization, and addressing nursing shortages.

摘要

背景

COVID-19 大流行在全球范围内对外科护理造成了前所未有的干扰,尤其是在资源匮乏的国家。我们旨在描述马拉维一家繁忙的三级医院在大流行前和大流行期间创伤临床结局的关联。

方法

我们分析了 2011 年至 2021 年 7 月期间在马拉维利隆圭的卡姆祖中心医院就诊的创伤患者。排除烧伤患者。我们根据患者就诊时间(定义为 2020 年 3 月 11 日,即世界卫生组织正式指定的日期)将其分为大流行前和大流行期间。我们使用逻辑回归模型估计基于就诊的死亡调整后的优势比。

结果

在研究期间共有 137867 名患者就诊,其中大流行期间有 13526 名患者。在大流行期间,患者更可能年龄较大(平均 28 岁比 25 岁,p<0.001)、男性(79%比 74%,p<0.001),且更可能以创伤性脑损伤(TBI)为主要损伤(9.7%比 4.9%,p<0.001)。大流行期间的创伤相关死亡率更高,为 3.7%比 2.1%(p<0.001)。与大流行前就诊相比,大流行期间的死亡率比值比为 1.28(95%置信区间 1.06,1.53),调整因素包括年龄、性别、初始 AVPU 评分、转移状态、损伤类型和机制。

结论

在资源匮乏的环境中,三级创伤中心在大流行期间,尽管患者人数减少,但调整后的创伤相关死亡率显著增加。迫切需要进一步研究为未来的大流行做准备。潜在的改进目标包括改善院前护理和转运、计划重症监护利用、以及解决护理人员短缺问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fdf/9244557/011a7ea51dbc/268_2022_6636_Fig1_HTML.jpg

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