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动物的冷冻保存与人体冷冻技术:当前技术进展、困难及可能的研究方向

Cryopreservation of Animals and Cryonics: Current Technical Progress, Difficulties and Possible Research Directions.

作者信息

Ekpo Marlene Davis, Boafo George Frimpong, Gambo Suleiman Shafiu, Hu Yuying, Liu Xiangjian, Xie Jingxian, Tan Songwen

机构信息

Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, China.

Department of Orthopedic Surgery, The Second Xiangya Hospital of Central South University, Central South University, Changsha, China.

出版信息

Front Vet Sci. 2022 Jun 9;9:877163. doi: 10.3389/fvets.2022.877163. eCollection 2022.

DOI:10.3389/fvets.2022.877163
PMID:35754544
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9219731/
Abstract

The basis of cryonics or medical cryopreservation is to safely store a legally dead subject until a time in the future when technology and medicine will permit reanimation after eliminating the disease or cause of death. Death has been debunked as an event occurring after cardiac arrest to a process where interjecting its progression can allow for reversal when feasible. Cryonics technology artificially halts further damages and injury by restoring respiration and blood circulation, and rapidly reducing temperature. The body can then be preserved at this extremely low temperature until the need for reanimation. Presently, the area has attracted numerous scientific contributions and advancement but the practice is still flooded with challenges. This paper presents the current progression in cryonics research. We also discuss obstacles to success in the field, and identify the possible solutions and future research directions.

摘要

人体冷冻技术或医学低温保存的基础是安全储存法律上已判定死亡的对象,直到未来某个时候,技术和医学能够在消除疾病或死亡原因后使其复苏。死亡已不再被视为心脏骤停后发生的一个事件,而是一个过程,在可行的情况下,介入这个过程的进展可以实现逆转。人体冷冻技术通过恢复呼吸和血液循环,并迅速降低温度,人为地阻止进一步的损伤。然后,身体可以在这个极低的温度下保存,直到需要复苏。目前,该领域已经吸引了众多的科学贡献和进展,但实践中仍然充满挑战。本文介绍了人体冷冻技术研究的当前进展。我们还讨论了该领域成功面临的障碍,并确定了可能的解决方案和未来的研究方向。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/203c/9219731/a25484e1a41c/fvets-09-877163-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/203c/9219731/a25484e1a41c/fvets-09-877163-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/203c/9219731/a25484e1a41c/fvets-09-877163-g0001.jpg

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Int J Mol Sci. 2022 Feb 27;23(5):2639. doi: 10.3390/ijms23052639.
2
Analysis of Cryopreservation Protocols and Their Harmful Effects on the Endothelial Integrity of Human Corneas.分析冷冻保存方案及其对人眼角膜内皮完整性的有害影响。
Int J Mol Sci. 2021 Nov 22;22(22):12564. doi: 10.3390/ijms222212564.
3
Iptakalim improves cerebral microcirculation in mice after ischemic stroke by inhibiting pericyte contraction.
依帕司他通过抑制周细胞收缩改善缺血性脑卒中后小鼠的脑微循环。
Acta Pharmacol Sin. 2022 Jun;43(6):1349-1359. doi: 10.1038/s41401-021-00784-4. Epub 2021 Oct 25.
4
Bioinspired materials and technology for advanced cryopreservation.仿生材料与技术在先进低温保存中的应用
Trends Biotechnol. 2022 Jan;40(1):93-106. doi: 10.1016/j.tibtech.2021.06.004. Epub 2021 Jul 5.
5
Advances in tissue engineering of vasculature through three-dimensional bioprinting.通过三维生物打印实现的血管组织工程进展。
Dev Dyn. 2021 Dec;250(12):1717-1738. doi: 10.1002/dvdy.385. Epub 2021 Jul 2.
6
3D Bioprinting of Vascularized Tissues for and Applications.用于[具体应用场景未给出]和[具体应用场景未给出]应用的血管化组织的3D生物打印
Front Bioeng Biotechnol. 2021 May 13;9:664188. doi: 10.3389/fbioe.2021.664188. eCollection 2021.
7
Accelerating cryoprotectant diffusion kinetics improves cryopreservation of pancreatic islets.加速抗冻保护剂扩散动力学可提高胰岛的冷冻保存效果。
Sci Rep. 2021 May 17;11(1):10418. doi: 10.1038/s41598-021-89853-6.
8
Stem cell treatment improves post stroke neurological outcomes: a comparative study in male and female rats.干细胞治疗改善中风后神经功能预后:雄性和雌性大鼠的对比研究。
Stroke Vasc Neurol. 2021 Dec;6(4):519-527. doi: 10.1136/svn-2020-000834. Epub 2021 Mar 19.
9
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Nanobiomedicine (Rij). 2020 Dec 29;7:1849543520983173. doi: 10.1177/1849543520983173. eCollection 2020 Jan-Dec.