Bejcek Alexis, Owens Justin, Marella Aditi, George Aneesh
Department of Medicine, Baylor Scott & White Medical Center - Temple, Temple, Texas.
Department of Medicine, Des Moines University, Des Moines, Iowa.
Proc (Bayl Univ Med Cent). 2022 Apr 12;35(4):555-556. doi: 10.1080/08998280.2022.2058831. eCollection 2022.
Nocardiosis is caused by various strains of the genus a gram-positive, acid-fast bacillus found in organic matter. Disseminated nocardiosis with central nervous system involvement is a rare infection that is most commonly seen in immunocompromised patients. We present a case of a 67-year-old veteran with stage IV adenocarcinoma of the lung undergoing chemotherapy who presented with new cavitary pulmonary lesions. Three weeks into his hospitalization, a sputum culture with acid-fast staining returned positive for . A subsequent computed tomography scan of the head demonstrated numerous rim-enhancing lesions presumed to be due to disseminated nocardiosis with central nervous system involvement. Disseminated nocardiosis has a high mortality rate, making prompt detection and treatment paramount for these patients. Our case highlights the importance of considering central nervous system involvement in the evaluation of a patient with nocardiosis.
诺卡菌病由诺卡菌属的多种菌株引起，诺卡菌是一种存在于有机物中的革兰氏阳性、抗酸杆菌。播散性诺卡菌病累及中枢神经系统是一种罕见的感染，最常见于免疫功能低下的患者。我们报告一例67岁患有IV期肺腺癌且正在接受化疗的退伍军人，该患者出现了新的肺部空洞性病变。住院三周后，痰培养及抗酸染色显示[具体诺卡菌名称]呈阳性。随后的头部计算机断层扫描显示有许多环形强化病变，推测是由于播散性诺卡菌病累及中枢神经系统所致。播散性诺卡菌病死亡率很高，因此对这些患者进行及时检测和治疗至关重要。我们的病例强调了在评估诺卡菌病患者时考虑中枢神经系统受累情况的重要性。
