Department of Microbiology, Harrogate and District Hospital, Lancaster Park Road, Harrogate, North Yorkshire, HG2 7SX, UK.
J Med Microbiol. 2010 Feb;59(Pt 2):224-230. doi: 10.1099/jmm.0.011593-0. Epub 2009 Oct 1.
Nocardia cyriacigeorgica is a common environmental organism. It has been isolated from clinical samples in Europe, Asia and North America, predominantly from respiratory samples but also from samples from several other sites. We present a case report of an 85-year-old female patient in the UK who was found to have a multi-focal soft-tissue infection from which N. cyriacigeorgica was isolated. She had a background history of chronic obstructive pulmonary disease and corticosteroid use for polymyalgia rheumatica. During the course of her treatment echocardiography showed the presence of a mobile heart mass attached to a valve leaflet, a major Dukes criterion for endocarditis. We suggest that in cases of disseminated Nocardia infection, endocarditis should be tested for, particularly in cases failing to respond to treatment. We also review previous reports of both N. cyriacigeorgica infection, and of endocarditis due to Nocardia species and related genera.
触球诺卡氏菌是一种常见的环境生物体。它已在欧洲、亚洲和北美洲的临床样本中分离出来，主要来自呼吸道样本，但也来自其他几个部位的样本。我们报告了一例英国 85 岁女性患者的病例，该患者被发现患有多处软组织感染，从中分离出触球诺卡氏菌。她有慢性阻塞性肺疾病的病史和用于治疗风湿性多肌痛的皮质类固醇。在治疗过程中，超声心动图显示存在附着在瓣叶上的可移动心脏肿块，这是心内膜炎的主要 Dukes 标准之一。我们建议，在出现诺卡氏菌播散性感染的情况下，应检查心内膜炎，特别是在治疗无效的情况下。我们还回顾了触球诺卡氏菌感染以及诺卡氏菌属和相关属引起的心内膜炎的以往报告。
