Woodside B, Millelire L
Physiol Behav. 1987;39(3):291-5. doi: 10.1016/0031-9384(87)90224-1.
A modification of the two-choice diet paradigm was used to determine whether female rats would self-select high levels of calcium at different times in a reproductive episode. A 2 X 2 X 5 (reproductive state X diet X time) design was used to compare the relative calcium intake of impregnated and non-impregnated rats given ad lib access to a calcium deficient or calcium sufficient diet together with demineralised water and a 2.4% calcium lactate solution over five weeks. For the impregnated groups, this time period comprised three weeks of pregnancy and two weeks of lactation. The results showed that during lactation the impregnated animals maintained on the calcium deficient diet consumed a greater amount of calcium solution relative to water intake than any other group. This increase in relative calcium solution intake occurred early in lactation and appeared not to correlate with increases in milk production.
采用两选饮食模式的一种变体来确定雌性大鼠在生殖周期的不同时间是否会自行选择高水平的钙。采用2×2×5（生殖状态×饮食×时间）设计，比较怀孕和未怀孕大鼠在五周内自由摄取缺钙或补钙饮食以及去离子水和2.4%乳酸钙溶液时的相对钙摄入量。对于怀孕组，这段时间包括三周的孕期和两周的哺乳期。结果表明，在哺乳期，食用缺钙饮食的怀孕动物相对于水的摄入量消耗了比其他任何组都更多的钙溶液。相对钙溶液摄入量的这种增加发生在哺乳期早期，并且似乎与产奶量的增加无关。
