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瘦鼠和肥胖大鼠的泌乳:自助餐式喂养及饮食性肥胖对乳汁成分的影响。

Lactation in lean and obese rats: effect of cafeteria feeding and of dietary obesity on milk composition.

作者信息

Rolls B A, Gurr M I, van Duijvenvoorde P M, Rolls B J, Rowe E A

出版信息

Physiol Behav. 1986;38(2):185-90. doi: 10.1016/0031-9384(86)90153-8.

DOI:10.1016/0031-9384(86)90153-8
PMID:3797485
Abstract

Changes in milk composition associated with maternal dietary obesity and cafeteria feeding were investigated. Protein, lactose and fat contents, and the fat composition, were determined for lean and obese rats given a cafeteria diet at different stages of reproduction. Feeding the cafeteria diet during lactation resulted in an increase in long-chain fatty acids and a fall in the characteristic medium-chain fatty acids. This effect was modified by obesity and the diet during pregnancy. Feeding the cafeteria diet in lactation reduced the milk protein and increased the fat. The milk of obese rats contained more energy, with more fat but less protein than that of lean rats. Increases in fat and long-chain fatty acid content, and decreases in protein and medium-chain fatty acid content of the milk were correlated with increased maternal intake of energy, total fat and long-chain fatty acids. Thus, the greatest influence on milk composition is exerted by the maternal diet during lactation. However, these effects are modified by pre-existing maternal obesity and the diet during pregnancy.

摘要

研究了与母体饮食肥胖和自助餐式喂养相关的乳汁成分变化。测定了在不同生殖阶段给予自助餐式饮食的瘦鼠和肥胖大鼠的蛋白质、乳糖和脂肪含量以及脂肪组成。哺乳期给予自助餐式饮食会导致长链脂肪酸增加,特征性中链脂肪酸减少。这种效应会因肥胖和孕期饮食而改变。哺乳期给予自助餐式饮食会降低乳汁蛋白质含量并增加脂肪含量。肥胖大鼠的乳汁比瘦鼠的乳汁含有更多能量,脂肪更多但蛋白质更少。乳汁中脂肪和长链脂肪酸含量的增加以及蛋白质和中链脂肪酸含量的减少与母体能量、总脂肪和长链脂肪酸摄入量的增加相关。因此,对乳汁成分影响最大的是哺乳期的母体饮食。然而,这些效应会因母体预先存在的肥胖和孕期饮食而改变。

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