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本文引用的文献

1
Association of Refractory Pain in the Acute Phase After Subarachnoid Hemorrhage With Continued Outpatient Opioid Use.蛛网膜下腔出血急性期难治性疼痛与门诊持续使用阿片类药物的关联。
Neurology. 2021 May 11;96(19):e2355-e2362. doi: 10.1212/WNL.0000000000011906. Epub 2021 Mar 25.
2
Association of Dexamethasone with Shunt Requirement, Early Disability, and Medical Complications in Aneurysmal Subarachnoid Hemorrhage.地塞米松与动脉瘤性蛛网膜下腔出血患者分流需求、早期残疾和医疗并发症的相关性。
Neurocrit Care. 2021 Jun;34(3):760-768. doi: 10.1007/s12028-020-01059-2. Epub 2020 Aug 26.
3
The burden of headache following aneurysmal subarachnoid hemorrhage: a prospective single-center cross-sectional analysis.动脉瘤性蛛网膜下腔出血后头痛的负担:一项前瞻性单中心横断面分析。
Acta Neurochir (Wien). 2020 Apr;162(4):893-903. doi: 10.1007/s00701-020-04235-7. Epub 2020 Feb 4.
4
When Expectancies Are Violated: A Functional Magnetic Resonance Imaging Study.当期望被违背时:一项功能磁共振成像研究。
Clin Pharmacol Ther. 2019 Dec;106(6):1246-1252. doi: 10.1002/cpt.1587. Epub 2019 Sep 10.
5
Treating Therapy-Resistant Headache After Aneurysmal Subarachnoid Hemorrhage with Acupuncture.针刺治疗动脉瘤性蛛网膜下腔出血后治疗抵抗性头痛。
Neurocrit Care. 2019 Oct;31(2):434-438. doi: 10.1007/s12028-019-00718-3.
6
Perioperative opioid analgesia-when is enough too much? A review of opioid-induced tolerance and hyperalgesia.围手术期阿片类镇痛药——何时多即是少?阿片类药物诱导的耐受和痛觉过敏的综述。
Lancet. 2019 Apr 13;393(10180):1558-1568. doi: 10.1016/S0140-6736(19)30430-1.
7
Virtual Reality and Medical Inpatients: A Systematic Review of Randomized, Controlled Trials.虚拟现实与住院患者:随机对照试验的系统评价
Innov Clin Neurosci. 2017 Feb 1;14(1-2):14-21. eCollection 2017 Jan-Feb.
8
The Longitudinal Course of Pain and Analgesic Therapy Following Aneurysmal Subarachnoid Hemorrhage: A Cohort Study.颅内动脉瘤性蛛网膜下腔出血后疼痛和镇痛治疗的纵向病程:一项队列研究。
Headache. 2016 Nov;56(10):1617-1625. doi: 10.1111/head.12908. Epub 2016 Oct 5.
9
Chronic pain disorders after critical illness and ICU-acquired opioid dependence: two clinical conundra.危重症后的慢性疼痛障碍与ICU获得性阿片类药物依赖:两个临床难题。
Curr Opin Crit Care. 2016 Oct;22(5):506-12. doi: 10.1097/MCC.0000000000000343.
10
Predictors of 30-day readmission after subarachnoid hemorrhage.蛛网膜下腔出血后 30 天再入院的预测因素。
Neurocrit Care. 2013 Dec;19(3):306-10. doi: 10.1007/s12028-013-9908-0.

使用沉浸式虚拟现实控制蛛网膜下腔出血后的疼痛和焦虑:一例报告

Pain Control and Anxiolysis After Subarachnoid Hemorrhage Using Immersive Virtual Reality: A Case Report.

作者信息

Kardon Adam, Murray Robert S, Khalid Mazhar, Colloca Luana, Simard J Marc, Badjatia Neeraj, Murthi Sarah B, Morris Nicholas A

机构信息

Department of Neurology, University of Maryland School of Medicine, Baltimore, MD, USA.

Program in Trauma, R Adams Cowley Shock Trauma Center, Baltimore, MD, USA.

出版信息

Neurohospitalist. 2022 Jul;12(3):563-566. doi: 10.1177/19418744221099412. Epub 2022 May 12.

DOI:10.1177/19418744221099412
PMID:35755230
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9214923/
Abstract

Debilitating headache persists after acute aneurysmal subarachnoid hemorrhage (SAH). Despite high prevalence, little is known regarding optimal treatment strategies for SAH-related headache. Nonpharmacologic adjunctive therapies are emerging as tools to help treat pain and limit opioid exposure in the hospital. Virtual reality (VR) is an immersive audiovisual experience that has been shown to reduce pain perception in other patient populations. The role of VR in acute brain injury is unknown. Here we report a patient with SAH who suffered from persistent headache during her hospitalization despite escalation of analgesic pharmacotherapy. A trial of VR was used as an adjunct to medication over four days. The patient reported subjective improvement in pain and anxiety. VR may provide additional analgesia and anxiolysis over pharmacologic measures alone and warrants further study in patients with acute brain injury.

摘要

急性动脉瘤性蛛网膜下腔出血(SAH)后,使人虚弱的头痛仍持续存在。尽管患病率很高,但对于SAH相关头痛的最佳治疗策略却知之甚少。非药物辅助治疗正逐渐成为帮助治疗疼痛和限制住院期间阿片类药物使用的手段。虚拟现实(VR)是一种沉浸式视听体验,已被证明可降低其他患者群体的疼痛感知。VR在急性脑损伤中的作用尚不清楚。在此,我们报告一名SAH患者,尽管镇痛药物治疗不断升级,但在住院期间仍遭受持续性头痛。在四天时间里,将VR试验用作药物治疗的辅助手段。患者报告疼痛和焦虑有主观改善。VR可能比单纯的药物治疗措施提供额外的镇痛和抗焦虑作用,值得在急性脑损伤患者中进一步研究。