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成人松果体细胞瘤(一种成人罕见脑肿瘤)内镜活检后的放射治疗:病例报告及文献综述

Radiotherapy After Endoscopic Biopsy in an Adult with Pineocytoma, the Rare Brain Tumor in an Adult: A Case Report and Literature Review.

作者信息

Hsieh Chi-Chih, Chen Jui-Sheng

机构信息

Department of Neurosurgery, E-Da Hospital, I-Shou University, Kaohsiung, Taiwan.

出版信息

Int Med Case Rep J. 2022 Jun 18;15:307-311. doi: 10.2147/IMCRJ.S367293. eCollection 2022.

DOI:10.2147/IMCRJ.S367293
PMID:35755243
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9215869/
Abstract

Tumors in the pineal region usually present with acute hydrocephalus. Histologic diagnosis is most important, as it greatly influences treatment, because over 17 tumor types occur in this area. Biopsies of these lesions play an important role in further management. are benign and rare tumors that typically exhibit a slow progression. However, the appropriate treatment for pineocytoma varies. Surgical excision was considered for good long-term outcomes; however, this may not always be possible. Radiotherapy also appears to be effective in patients with residual pineocytomas. We report a case of pineocytoma with hemorrhagic transformation and complicated hydrocephalus. The patient refused to undergo aggressive tumor excision. Thus, the patient only underwent endoscopic biopsy and external ventricular drain (EVD) implantation, but the outcome was acceptable. In addition, we reviewed the current management strategies for pineocytomas in the literature.

摘要

松果体区肿瘤通常表现为急性脑积水。组织学诊断最为重要,因为它对治疗有很大影响,该区域可发生超过17种肿瘤类型。这些病变的活检在进一步治疗中起着重要作用。松果体细胞瘤是良性且罕见的肿瘤,通常进展缓慢。然而,松果体细胞瘤的适当治疗方法各不相同。为获得良好的长期疗效考虑手术切除;然而,这并非总是可行。放疗对残留松果体细胞瘤患者似乎也有效。我们报告一例发生出血性转化并伴有复杂性脑积水的松果体细胞瘤病例。患者拒绝接受积极的肿瘤切除。因此,患者仅接受了内镜活检和脑室外引流(EVD)植入,但结果尚可。此外,我们回顾了文献中松果体细胞瘤的当前治疗策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b53/9215869/86a5fa96a575/IMCRJ-15-307-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b53/9215869/15e6929634e7/IMCRJ-15-307-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b53/9215869/436a0db567a8/IMCRJ-15-307-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b53/9215869/40c9aaf1aedd/IMCRJ-15-307-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b53/9215869/c14356ea0a48/IMCRJ-15-307-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b53/9215869/86a5fa96a575/IMCRJ-15-307-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b53/9215869/15e6929634e7/IMCRJ-15-307-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b53/9215869/436a0db567a8/IMCRJ-15-307-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b53/9215869/40c9aaf1aedd/IMCRJ-15-307-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b53/9215869/c14356ea0a48/IMCRJ-15-307-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b53/9215869/86a5fa96a575/IMCRJ-15-307-g0005.jpg

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本文引用的文献

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Pineal Gland Tumors: A Review.松果体肿瘤:综述
Cancers (Basel). 2021 Mar 27;13(7):1547. doi: 10.3390/cancers13071547.
2
The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary.2016 年世界卫生组织中枢神经系统肿瘤分类:概述。
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Endoscopic versus stereotactic procedure for pineal tumour biopsies: Comparative review of the literature and learning from a 25-year experience.松果体肿瘤活检的内镜手术与立体定向手术:文献比较综述及基于25年经验的总结
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Long-term radiosurgical control of subtotally resected adult pineocytomas.成人松果体细胞瘤次全切除术后的长期放射外科控制。
J Neurosurg. 2012 Aug;117(2):212-7. doi: 10.3171/2012.5.JNS1251. Epub 2012 Jun 15.
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Long term outcome of adolescent and adult patients with pineal parenchymal tumors treated with fractionated radiotherapy between 1982 and 2003--a single institution's experience.1982 年至 2003 年间接受分次放疗的青少年和成年患者的松果体实质肿瘤的长期结果--单机构经验。
Radiat Oncol. 2010 Dec 26;5:122. doi: 10.1186/1748-717X-5-122.
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Factors influencing overall survival rates for patients with pineocytoma.影响松果体细胞瘤患者总生存率的因素。
J Neurooncol. 2010 Nov;100(2):255-60. doi: 10.1007/s11060-010-0189-6. Epub 2010 May 12.
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Pineal gland tumors: experience from the SEER database.松果体瘤:来自监测、流行病学和最终结果(SEER)数据库的经验
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J Neurosurg. 2004 May;100(5 Suppl Pediatrics):437-41. doi: 10.3171/ped.2004.100.5.0437.
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The role of neuroendoscopy in the treatment of pineal region tumors.神经内镜在松果体区肿瘤治疗中的作用。
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Pineal region tumors in children.儿童松果体区肿瘤
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