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COVID-19 大流行期间托斯卡纳地区急性心肌梗死、卒中和心力衰竭住院人数的变化:一项中断时间序列研究。

Changes in Acute Myocardial Infarction, Stroke, and Heart Failure Hospitalizations During COVID-19 Pandemic in Tuscany-An Interrupted Time Series Study.

机构信息

Hamburg Center for Health Economics, University of Hamburg, Hamburg, Germany.

OptiMedis AG, Hamburg, Germany.

出版信息

Int J Public Health. 2022 Jun 8;67:1604319. doi: 10.3389/ijph.2022.1604319. eCollection 2022.

DOI:10.3389/ijph.2022.1604319
PMID:35755955
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9216172/
Abstract

We evaluate the impact of the COVID-19 pandemic on unplanned hospitalization rates for patients without COVID-19, including their length of stay, and in-hospital mortality, overall, and for acute myocardial infarction (AMI), stroke, and heart failure in the Tuscany region of Italy. We carried out a population-based controlled interrupted time series study using segmented linear regression with an autoregressive error term based on admissions data from all public hospitals in Tuscany. The primary outcome measure was weekly hospitalization rates; secondary outcomes included length of stay, and in-hospital mortality. The implementation of the pandemic-related mitigation measures and fear of infection was associated with large decreases in inpatient hospitalization rates overall (-182 [-234, -130]), unplanned hospitalization (-39 [-51, -26]), and for AMI (-1.32 [-1.98, -0.66]), stroke (-1.51 [-2.56, -0.44]), and heart failure (-8.7 [-11.1, -6.3]). Average length of stay and percent in-hospital mortality for select acute medical conditions did not change significantly. In Tuscany, Italy, the COVID-19 pandemic was associated with large reductions in hospitalization rates overall, as well as for heart failure, and the time sensitive conditions of AMI and stroke during the months January to July 2020.

摘要

我们评估了 COVID-19 大流行对无 COVID-19 的患者非计划性住院率的影响,包括其住院时间和住院死亡率,总体而言,以及在意大利托斯卡纳地区的急性心肌梗死 (AMI)、中风和心力衰竭。我们开展了一项基于人群的对照中断时间序列研究,使用基于托斯卡纳所有公立医院入院数据的分段线性回归和自回归误差项,采用自动回归误差项。主要结局指标是每周住院率;次要结局包括住院时间和住院死亡率。与大流行相关的缓解措施的实施和对感染的恐惧与住院患者总体住院率的大幅下降有关 (-182[-234,-130])、非计划性住院率 (-39[-51,-26])以及 AMI(-1.32[-1.98,-0.66])、中风(-1.51[-2.56,-0.44])和心力衰竭(-8.7[-11.1,-6.3])。选择的急性医疗状况的平均住院时间和住院死亡率没有明显变化。在意大利托斯卡纳,COVID-19 大流行与 2020 年 1 月至 7 月期间总体住院率的大幅下降以及心力衰竭以及 AMI 和中风等时间敏感状况有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1a5/9216172/2ee17a628fdd/ijph-67-1604319-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1a5/9216172/2ee17a628fdd/ijph-67-1604319-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1a5/9216172/2ee17a628fdd/ijph-67-1604319-g001.jpg

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