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西班牙南部 COVID-19 大流行对冠状动脉和脑血管疾病的影响:中断时间序列分析。

COVID-19 pandemic on coronary artery and cerebrovascular diseases in Southern Spain: interrupted time series analysis.

机构信息

Department of Nursing, Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, Spain.

出版信息

Eur Rev Med Pharmacol Sci. 2023 Apr;27(7):3208-3217. doi: 10.26355/eurrev_202304_31955.

DOI:10.26355/eurrev_202304_31955
PMID:37070925
Abstract

OBJECTIVE

Healthcare systems have been put under intense pressure by the COVID-19 pandemic, although some studies have shown a decline in hospital admissions for cardiovascular and cerebrovascular diseases during the first and second wave of the pandemic. In addition, studies analyzing gender and procedural differences are scarce. The present study aimed to determine the impact of the pandemic on hospital admissions for acute myocardial infarction (AMI) and cerebrovascular disease (CVD) in Andalusia (Spain) and analyzed differences by gender and by percutaneous coronary interventions performed.

PATIENTS AND METHODS

An interrupted time series analysis of AMI and CVD hospital admissions in Andalusia (Spain) was carried out to measure the impact of the COVID-19 outbreak. AMI and CVD cases admitted daily in public hospitals of Andalusia between January 2018 and December 2020 were included.

RESULTS

During the pandemic, significant reductions in AMI [-19%; 95% confidence interval (CI): (-29%, -9%), p<0.001] and CVD [-17%; 95% CI: (-26%, -9%); p<0.01] in daily hospital admissions were observed. Differences were also produced according to the diagnosis (ST-Elevation Myocardial Infarction, Non-ST-Elevation Myocardial Infarction, other AMI and stroke), with a greater reduction in females for AMI and in males for CVD. Although there were more percutaneous coronary interventions during the pandemic, no significant reductions were observed.

CONCLUSIONS

A decline in AMI and CVD daily hospital admissions during the first and second wave of COVID-19 pandemic was noted. Gender differences were observed, but no clear impact was observed in percutaneous interventions.

摘要

目的

尽管一些研究表明,在 COVID-19 大流行的第一波和第二波期间,心血管和脑血管疾病的住院人数有所下降,但医疗系统仍承受着巨大压力。此外,分析性别和程序差异的研究很少。本研究旨在确定 COVID-19 大流行对安达卢西亚(西班牙)急性心肌梗死(AMI)和脑血管疾病(CVD)住院人数的影响,并分析了性别和经皮冠状动脉介入治疗的差异。

患者和方法

对安达卢西亚(西班牙)的 AMI 和 CVD 住院人数进行了一项中断时间序列分析,以衡量 COVID-19 爆发的影响。纳入了 2018 年 1 月至 2020 年 12 月期间安达卢西亚公立医院每天收治的 AMI 和 CVD 病例。

结果

在大流行期间,AMI(-19%;95%置信区间:[-29%,-9%];p<0.001)和 CVD(-17%;95%置信区间:[-26%,-9%];p<0.01)的每日住院人数均显著减少。根据诊断(ST 段抬高型心肌梗死、非 ST 段抬高型心肌梗死、其他 AMI 和中风)也产生了差异,女性的 AMI 减少幅度更大,男性的 CVD 减少幅度更大。尽管在大流行期间进行了更多的经皮冠状动脉介入治疗,但没有观察到显著减少。

结论

在 COVID-19 大流行的第一波和第二波期间,AMI 和 CVD 的每日住院人数有所下降。观察到了性别差异,但经皮介入治疗没有明显影响。

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