Schulte Timo, Bohnet-Joschko Sabine
Witten/Herdecke University, Germany.
Int J Integr Care. 2022 Jun 16;22(2):23. doi: 10.5334/ijic.5543. eCollection 2022 Apr-Jun.
Health systems in high-income countries face a variety of challenges calling for a systemic approach to improve quality and efficiency. Putting people in the centre is the main idea of the WHO model of people-centred and integrated health services. Integrating health services is fuelled by an integration of health data with great potentials for decision support based on big data analytics. The research question of this paper is "How can big data analytics support people-centred and integrated health services?"
A scoping review following the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses - Scoping Review (PRISMA-ScR) statement was conducted to gather information on how big data analytics can support people-centred and integrated health services. The results were summarized in a role model of a people-centred and integrated health services platform illustrating which data sources might be integrated and which types of analytics might be applied to support the strategies of the people-centred and integrated health services framework to become more integrated across the continuum of care. Additional rapid literature reviews were conducted to generate frequency distributions of the most often used data types and analytical methods in the medical literature. Finally, the main challenges connected with big data analytics were worked out based on a content analysis of the results from the scoping literature review.
Based on the results from the rapid literature reviews the most often used data sources for big data analytics (BDA) in healthcare were biomarkers (39.3%) and medical images (30.9%). The most often used analytical models were support vector machines (27.3%) and neural networks (20.4%). The people-centred and integrated health services framework defines different strategic interventions for health services to become more integrated. To support all aspects of these interventions a comparably integrated platform of health-related data would be needed, so that a role model labelled as people-centred health platform was developed. Based on integrated data the results of the scoping review (n = 72) indicate, that big data analytics could for example support the strategic intervention of tailoring personalized health plans (43.1%), e.g. by predicting individual risk factors for different therapy options. Also BDA might enhance clinical decision support tools (31.9%), e.g. by calculating risk factors for disease uptake or progression. BDA might also assist in designing population-based services (26.4% by clustering comparable individuals in manageable risk groups e.g. mentored by specifically trained, non-medical professionals. The main challenges of big data analytics in healthcare were categorized in regulatory, (information-) technological, methodological, and cultural issues, whereas methodological challenges were mentioned most often (55.0%), followed by regulatory challenges (43.7%).
The BDA applications presented in this literature review are based on findings which have already been published. For some important components of the framework on people-centred care like enhancing the role of community care or establishing intersectoral partnerships between health and social care institutions only few examples of enabling big data analytical tools were found in the literature. Quite the opposite does this mean that these strategies have less potential value, but rather that the source systems in these fields need to be further developed to be suitable for big data analytics.
Big data analytics can support people-centred and integrated health services e.g. by patient similarity stratifications or predictions of individual risk factors. But BDA fails to unfold its full potential until data source systems are still disconnected and actions towards a comprehensive and people-centred health-related data platform are politically insufficiently incentivized. This work highlighted the potential of big data analysis in the context of the model of people-centred and integrated health services, whereby the role model of the person-centered health platform can be used as a blueprint to support strategies to improve person-centered health care. Likely because health data is extremely sensitive and complex, there are only few practical examples of platforms to some extent already capable of merging and processing people-centred big data, but the integration of health data can be expected to further proceed so that analytical opportunities might also become reality in the near future.
高收入国家的卫生系统面临着各种挑战,需要采用系统方法来提高质量和效率。以人为本是世界卫生组织以人为本的综合卫生服务模式的核心思想。卫生服务的整合是由卫生数据的整合推动的,基于大数据分析的卫生数据具有巨大的决策支持潜力。本文的研究问题是“大数据分析如何支持以人为本的综合卫生服务?”
按照系统评价和Meta分析的首选报告项目——范围综述(PRISMA-ScR)声明的建议进行了一项范围综述,以收集有关大数据分析如何支持以人为本的综合卫生服务的信息。结果总结在一个以人为本的综合卫生服务平台的角色模型中,该模型说明了哪些数据源可能被整合,以及可能应用哪些类型的分析来支持以人为本的综合卫生服务框架的策略,使其在连续护理过程中更加整合。还进行了额外的快速文献综述,以生成医学文献中最常用的数据类型和分析方法的频率分布。最后,基于对范围文献综述结果的内容分析,梳理出与大数据分析相关的主要挑战。
根据快速文献综述的结果,医疗保健中大数据分析(BDA)最常用的数据源是生物标志物(39.3%)和医学图像(30.9%)。最常用的分析模型是支持向量机(27.3%)和神经网络(20.4%)。以人为本的综合卫生服务框架为卫生服务变得更加整合定义了不同的战略干预措施。为了支持这些干预措施的各个方面,需要一个相对整合的健康相关数据平台,因此开发了一个名为以人为本的健康平台的角色模型。基于整合数据,范围综述(n = 72)的结果表明,大数据分析例如可以支持制定个性化健康计划的战略干预措施(43.1%),例如通过预测不同治疗方案的个体风险因素。BDA还可能增强临床决策支持工具(31.9%),例如通过计算疾病发生或进展的风险因素。BDA还可能有助于设计基于人群的服务(26.4%),例如通过将可比个体聚类到可管理的风险组中,例如由经过专门培训的非医学专业人员指导。医疗保健中大数据分析的主要挑战分为监管、(信息)技术、方法和文化问题,其中方法挑战被提及的频率最高(55.0%),其次是监管挑战(43.7%)。
本综述中介绍的BDA应用基于已发表的研究结果。在以人为本的护理框架的一些重要组成部分中,如加强社区护理的作用或在卫生和社会护理机构之间建立部门间伙伴关系,在文献中仅发现了少数启用大数据分析工具的例子。这并不意味着这些策略的潜在价值较小,而是意味着这些领域的源系统需要进一步开发以适合大数据分析。
大数据分析可以支持以人为本的综合卫生服务,例如通过患者相似性分层或个体风险因素预测。但在数据源系统仍然脱节且对建立一个全面的、以人为本的健康相关数据平台的行动缺乏足够政治激励的情况下,BDA无法充分发挥其潜力。这项工作突出了大数据分析在以人为本的综合卫生服务模式背景下的潜力,可以将以人为本的健康平台的角色模型用作蓝图,以支持改善以人为本的医疗保健的策略。可能由于健康数据极其敏感和复杂,目前只有少数在一定程度上已经能够合并和处理以人为本的大数据的平台的实际示例,但健康数据的整合有望进一步推进,以便分析机会在不久的将来也可能成为现实。