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与急性重症哮喘相关的重症监护病房获得性肌无力

Intensive Care Unit Acquired Weakness Associated With Acute Severe Asthma.

作者信息

Borré-Naranjo Diana, Rodríguez-Yánez Tomás, Almanza-Hurtado Amilkar, Martínez-Ávila María Cristina, Dueñas-Castell Carmelo

机构信息

Department of Critical Care Medicine, Universidad de Cartagena, Cartagena, Colombia.

Department of Epidemiology and Public Health, Universidad de Cartagena, Cartagena, Colombia.

出版信息

Clin Med Insights Case Rep. 2022 Jun 20;15:11795476221106759. doi: 10.1177/11795476221106759. eCollection 2022.

DOI:10.1177/11795476221106759
PMID:35756357
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9218888/
Abstract

CONTEXT

Neuromuscular complications in the intensive care unit (ICU) are frequent, multifactorial, and clinically difficult to recognize during their acute phase. The physical examination is the starting point for identification.

CASE REPORT

We present a patient with a history of poorly controlled asthma who was admitted to the ICU with status asthmaticus. After 4 days of being under ventilatory support, he developed muscle weakness. The diagnostic approach made it possible to establish myopathic and neurological compromise through electrophysiology studies.

CONCLUSIONS

ICU-acquired weakness (ICUAW) can bring long-term consequences, early identification, and management, as well as preventive measures, are essential to minimize chronic disability and morbidity.

摘要

背景

重症监护病房(ICU)中的神经肌肉并发症很常见,具有多因素性,并且在急性期临床诊断困难。体格检查是识别的起点。

病例报告

我们报告一名哮喘控制不佳病史的患者,因哮喘持续状态入住ICU。在接受通气支持4天后,他出现了肌肉无力。通过电生理研究,诊断方法得以确定肌病和神经功能损害。

结论

ICU获得性肌无力(ICUAW)可带来长期后果,早期识别、管理以及预防措施对于将慢性残疾和发病率降至最低至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3094/9218888/55a8f6ecdc66/10.1177_11795476221106759-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3094/9218888/a9e7868142c7/10.1177_11795476221106759-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3094/9218888/55a8f6ecdc66/10.1177_11795476221106759-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3094/9218888/a9e7868142c7/10.1177_11795476221106759-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3094/9218888/55a8f6ecdc66/10.1177_11795476221106759-fig2.jpg

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本文引用的文献

1
Intensive Care Unit-Acquired Weakness: A Review of Recent Progress With a Look Toward the Future.重症监护病房获得性肌无力:近期进展回顾与未来展望
Front Med (Lausanne). 2020 Nov 23;7:559789. doi: 10.3389/fmed.2020.559789. eCollection 2020.
2
ICU-acquired weakness.ICU 获得性肌无力
Intensive Care Med. 2020 Apr;46(4):637-653. doi: 10.1007/s00134-020-05944-4. Epub 2020 Feb 19.
3
[Diagnostic tools of intensive care unit acquired weakness: a systematic review].[重症监护病房获得性肌无力的诊断工具:一项系统综述]
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2018 Dec;30(12):1154-1160. doi: 10.3760/cma.j.issn.2095-4352.2018.012.011.
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Corticosteroid use and intensive care unit-acquired weakness: a systematic review and meta-analysis.皮质类固醇的使用与重症监护病房获得性肌无力:系统评价和荟萃分析。
Crit Care. 2018 Aug 3;22(1):187. doi: 10.1186/s13054-018-2111-0.
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Risk factors for intensive care unit-acquired weakness: A systematic review and meta-analysis.重症监护病房获得性肌无力的危险因素:系统评价和荟萃分析。
Acta Neurol Scand. 2018 Aug;138(2):104-114. doi: 10.1111/ane.12964. Epub 2018 May 29.