Domashenko A D, Zhivogovskiĭ B D, Umanskiĭ S R, Khanson K P
Radiobiologiia. 1987 Mar-Apr;27(2):160-5.
Biosynthesis of chromatin proteins in thymus cells of irradiated rats has been studied. During the period immediately preceding DNA degradation, new proteins, which are not found in the chromatin of the control cells, are synthesized in the exposed thymocytes and enter the chromatin. Besides, the rate of biosynthesis of a large number of other chromatin proteins decreases. The data obtained indicate that interphase death of lymphoid cells is an active, genetically programmed process.
已对受辐照大鼠胸腺细胞中染色质蛋白的生物合成进行了研究。在DNA降解之前的这段时间里,受照射的胸腺细胞中合成了对照细胞染色质中未发现的新蛋白质,并进入染色质。此外,大量其他染色质蛋白的生物合成速率下降。所获得的数据表明,淋巴细胞的间期死亡是一个活跃的、由基因编程的过程。