Kumar Sushil, Rai Neha, Bansal Akash, Mittal Amit, Chandra Nimai Chand
Department of Biochemistry, All India Institute of Medical Sciences, Patna, 801507 India.
Department of Nursing, All India Institute of Medical Sciences, Patna, 801507 India.
Indian J Clin Biochem. 2023 Apr;38(2):182-192. doi: 10.1007/s12291-022-01054-8. Epub 2022 Jun 18.
COVID-19, a global pandemic that led to increased morbidity and mortality worldwide since its outcome at the end of the year 2019. A newly discovered variant of severe acute respiratory distress syndrome coronavirus-2 (SARS-CoV-2) was the arbitrator for spreading the syndrome by droplet transmission causing multi-organ failure in many occasions. A post-infection-pro-diabetic disposition was found evident in this study with the persistence of hepato-pancreatic aberrations in respect of reference range of tissue specific bio-markers in hospital admitted COVID-19 cases. The results of this study show that hyperglycemia is a risk factor in precipitating disease oriented complications to the patients with COVID-19 disease. A post-infection follow- up on glycemic-index and related complexities is a vital need to the COVID-19 infected convalescent subjects. Implementation of guidelines on social measure and awareness of anti-viral interventions may be the only way to prevent COVID-19 transmission.
自2019年底出现以来,新冠病毒病已成为一场全球大流行疾病,导致全球发病率和死亡率上升。一种新发现的严重急性呼吸综合征冠状病毒2(SARS-CoV-2)变种是通过飞沫传播该综合征的媒介,在许多情况下会导致多器官衰竭。本研究发现,在入院的新冠病毒病病例中,就组织特异性生物标志物的参考范围而言,肝胰腺异常持续存在,感染后糖尿病倾向明显。本研究结果表明,高血糖是新冠病毒病患者引发疾病相关并发症的一个危险因素。对新冠病毒感染康复者进行感染后血糖指数及相关复杂性的随访至关重要。实施社会措施指南和提高对抗病毒干预措施的认识可能是预防新冠病毒传播的唯一途径。