• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

机器学习与实验设计及其在化学工业产品创新中的应用

Machine learning and design of experiments with an application to product innovation in the chemical industry.

作者信息

Arboretti Rosa, Ceccato Riccardo, Pegoraro Luca, Salmaso Luigi, Housmekerides Chris, Spadoni Luca, Pierangelo Elisabetta, Quaggia Sara, Tveit Catherine, Vianello Sebastiano

机构信息

Department of Civil, Environmental and Architectural Engineering, Università degli Studi di Padova, Padua, Italy.

Department of Management and Engineering, Università degli Studi di Padova, Vicenza, Italy.

出版信息

J Appl Stat. 2021 Mar 26;49(10):2674-2699. doi: 10.1080/02664763.2021.1907840. eCollection 2022.

DOI:10.1080/02664763.2021.1907840
PMID:35757041
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9225671/
Abstract

Industrial statistics plays a major role in the areas of both quality management and innovation. However, existing methodologies must be integrated with the latest tools from the field of Artificial Intelligence. To this end, a background on the joint application of Design of Experiments (DOE) and Machine Learning (ML) methodologies in industrial settings is presented here, along with a case study from the chemical industry. A DOE study is used to collect data, and two ML models are applied to predict responses which performance show an advantage over the traditional modeling approach. Emphasis is placed on causal investigation and quantification of prediction uncertainty, as these are crucial for an assessment of the goodness and robustness of the models developed. Within the scope of the case study, the models learned can be implemented in a semi-automatic system that can assist practitioners who are inexperienced in data analysis in the process of new product development.

摘要

工业统计学在质量管理和创新领域都发挥着重要作用。然而,现有的方法必须与人工智能领域的最新工具相结合。为此,本文介绍了实验设计(DOE)和机器学习(ML)方法在工业环境中的联合应用背景,并给出了一个来自化学工业的案例研究。通过DOE研究来收集数据,并应用两个ML模型来预测响应,其性能优于传统建模方法。重点在于因果调查和预测不确定性的量化,因为这些对于评估所开发模型的优劣和稳健性至关重要。在案例研究范围内,所学习到的模型可以在半自动系统中实现,该系统可以在新产品开发过程中协助缺乏数据分析经验的从业者。

相似文献

1
Machine learning and design of experiments with an application to product innovation in the chemical industry.机器学习与实验设计及其在化学工业产品创新中的应用
J Appl Stat. 2021 Mar 26;49(10):2674-2699. doi: 10.1080/02664763.2021.1907840. eCollection 2022.
2
Artificial Intelligence-Based Traditional Chinese Medicine Assistive Diagnostic System: Validation Study.基于人工智能的中医辅助诊断系统:验证研究。
JMIR Med Inform. 2020 Jun 15;8(6):e17608. doi: 10.2196/17608.
3
Combining handcrafted features with latent variables in machine learning for prediction of radiation-induced lung damage.将机器学习中的手工特征与潜在变量相结合,以预测放射性肺损伤。
Med Phys. 2019 May;46(5):2497-2511. doi: 10.1002/mp.13497. Epub 2019 Apr 8.
4
Artificial neural networks in evaluation and optimization of modified release solid dosage forms.人工神经网络在改良释放固体制剂的评价和优化中的应用。
Pharmaceutics. 2012 Oct 18;4(4):531-50. doi: 10.3390/pharmaceutics4040531.
5
Digital Pharmaceutical Sciences.数字药物科学。
AAPS PharmSciTech. 2020 Jul 26;21(6):206. doi: 10.1208/s12249-020-01747-4.
6
Design of experiment (DOE) applied to artificial neural network architecture enables rapid bioprocess improvement.设计实验(DOE)应用于人工神经网络结构可实现快速生物工艺改进。
Bioprocess Biosyst Eng. 2021 Jun;44(6):1301-1308. doi: 10.1007/s00449-021-02529-3. Epub 2021 Feb 27.
7
[Integration of production-university-research based on artificial intelligence for technological innovation and transformation in gastrointestinal surgery].基于人工智能的产学研整合促进胃肠外科技术创新与转化
Zhonghua Wei Chang Wai Ke Za Zhi. 2020 Jun 25;23(6):557-561. doi: 10.3760/cma.j.cn.441530-20200305-00118.
8
Design of experiments (DoE) in pharmaceutical development.药物研发中的实验设计
Drug Dev Ind Pharm. 2017 Jun;43(6):889-901. doi: 10.1080/03639045.2017.1291672. Epub 2017 Feb 23.
9
Industry-scale application and evaluation of deep learning for drug target prediction.深度学习在药物靶点预测中的工业规模应用与评估
J Cheminform. 2020 Apr 19;12(1):26. doi: 10.1186/s13321-020-00428-5.
10
Optimization of the SAG Grinding Process Using Statistical Analysis and Machine Learning: A Case Study of the Chilean Copper Mining Industry.运用统计分析和机器学习优化半自磨机(SAG)研磨工艺:以智利铜矿业为例
Materials (Basel). 2023 Apr 19;16(8):3220. doi: 10.3390/ma16083220.

引用本文的文献

1
Healthcare workers' priorities of WHO snakebite strategic objectives for the control and prevention of snakebite envenoming in Ghana: A machine learning statistical design of experiment modeling.加纳医护人员对世界卫生组织蛇咬伤控制与预防战略目标的优先排序:基于机器学习的实验建模统计设计
PLoS Negl Trop Dis. 2025 Jul 10;19(7):e0013295. doi: 10.1371/journal.pntd.0013295. eCollection 2025 Jul.
2
A supervised machine learning statistical design of experiment approach to modeling the barriers to effective snakebite treatment in Ghana.一种用于对加纳有效蛇咬伤治疗障碍进行建模的有监督机器学习统计实验设计方法。
PLoS Negl Trop Dis. 2024 Dec 13;18(12):e0012736. doi: 10.1371/journal.pntd.0012736. eCollection 2024 Dec.

本文引用的文献

1
BiMM tree: A decision tree method for modeling clustered and longitudinal binary outcomes.BiMM树:一种用于对聚类和纵向二元结局进行建模的决策树方法。
Commun Stat Simul Comput. 2020;49(4):1004-1023. doi: 10.1080/03610918.2018.1490429. Epub 2018 Sep 12.
2
BiMM forest: A random forest method for modeling clustered and longitudinal binary outcomes.BiMM森林:一种用于对聚类和纵向二元结局进行建模的随机森林方法。
Chemometr Intell Lab Syst. 2019 Feb 15;185:122-134. doi: 10.1016/j.chemolab.2019.01.002. Epub 2019 Jan 11.
3
NeuralNetTools: Visualization and Analysis Tools for Neural Networks.神经网络工具:用于神经网络的可视化和分析工具。
J Stat Softw. 2018;85(11):1-20. doi: 10.18637/jss.v085.i11.
4
The application of machine learning algorithms in understanding the effect of core/shell technique on improving powder compactability.机器学习算法在理解核/壳技术对提高粉末压实性的影响中的应用。
Int J Pharm. 2019 Jan 30;555:368-379. doi: 10.1016/j.ijpharm.2018.11.039. Epub 2018 Nov 20.
5
How To Optimize Materials and Devices via Design of Experiments and Machine Learning: Demonstration Using Organic Photovoltaics.如何通过实验设计和机器学习优化材料与器件:以有机光伏为例的演示
ACS Nano. 2018 Aug 28;12(8):7434-7444. doi: 10.1021/acsnano.8b04726. Epub 2018 Jul 20.
6
Big data: Some statistical issues.大数据:一些统计学问题。
Stat Probab Lett. 2018 May;136:111-115. doi: 10.1016/j.spl.2018.02.015.
7
Confidence Intervals for Random Forests: The Jackknife and the Infinitesimal Jackknife.随机森林的置信区间:刀切法和无穷小刀切法
J Mach Learn Res. 2014 Jan;15(1):1625-1651.
8
Estimation and Accuracy after Model Selection.模型选择后的估计与准确性。
J Am Stat Assoc. 2014 Jul 1;109(507):991-1007. doi: 10.1080/01621459.2013.823775.
9
Artificial neural networks in evaluation and optimization of modified release solid dosage forms.人工神经网络在改良释放固体制剂的评价和优化中的应用。
Pharmaceutics. 2012 Oct 18;4(4):531-50. doi: 10.3390/pharmaceutics4040531.
10
Application of design of experiments and multilayer perceptrons neural network in the optimization of diclofenac sodium extended release tablets with Carbopol 71G.实验设计与多层感知器神经网络在含卡波姆71G双氯芬酸钠缓释片优化中的应用
Chem Pharm Bull (Tokyo). 2010 Jul;58(7):947-9. doi: 10.1248/cpb.58.947.