Department of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Department of Gynecology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Front Public Health. 2022 Jun 10;10:911377. doi: 10.3389/fpubh.2022.911377. eCollection 2022.
To explore the effects of osimertinib combined with pulmonary rehabilitation and health care training on pulmonary function, complications, and the quality of life (QOL) in patients after radical resection of lung cancer.
The data of 120 patients with radical resection of lung cancer admitted to from February 2020 to February 2021 were retrospectively analyzed. According to the order of admission, they were equally divided into group p and group q. All patients were given pulmonary rehabilitation and health care training, and group p was treated with osimertinib, while group q received the treatment of pemetrexed combined with cisplatin. The pulmonary function, the incidence of complications, and QOL between the two groups were compared.
Compared with group q, the pulmonary function was higher ( < 0.001), the incidence of complications was significantly lower ( < 0.05), and QOL scores were markedly higher in group p after treatment ( < 0.001).
The combination of osimertinib and pulmonary rehabilitation and health care training can improve the pulmonary function of patients with non-small cell lung cancer (NSCLC) with radical resection of lung cancer, and reduce their postoperative morbidity, thereby improving their QOL, which is conducive to reducing the patient's and society's medical burden.
探讨奥希替尼联合肺康复及保健训练对肺癌根治术后患者肺功能、并发症及生活质量（QOL）的影响。
回顾性分析 2020 年 2 月至 2021 年 2 月间收治的 120 例肺癌根治术患者的临床资料，按照入院顺序等分为 p 组和 q 组。两组患者均给予肺康复及保健训练，p 组在此基础上给予奥希替尼治疗，q 组给予培美曲塞联合顺铂治疗。比较两组患者的肺功能、并发症发生率及 QOL。
与 q 组相比，p 组治疗后肺功能更高（<0.001），并发症发生率显著更低（<0.05），QOL 评分更高（<0.001）。
奥希替尼联合肺康复及保健训练可改善肺癌根治术后非小细胞肺癌（NSCLC）患者的肺功能，降低术后发病率，提高患者 QOL，有利于减轻患者及社会的医疗负担。
