Pediatric and Congenital Cardiac Surgery Unit, Padova, Veneto, Italy.
Unit of Biostatistics, Department of Cardiac, Thoracic, Vascular Sciences, and Public Health, University of Padova Medical School, Italy.
World J Pediatr Congenit Heart Surg. 2022 Jul;13(4):485-494. doi: 10.1177/21501351221095424.
We conducted a systematic review and meta-analysis of the literature to assess the outcomes of surgery for the anomalous aortic origin of a coronary artery in children and young adults (<30 years). Thirteen publications were selected, including a total of 384 patients. Unroofing of the intramural segment was adopted in 92% (95% CI: 81%-98%) of cases, with pooled early and late mortality of 0% (95% CI: 0%-0.3%) and 0.1% (95% CI: 0%-1%), respectively. Reoperation for aortic regurgitation was anecdotal. Surgical management of anomalous aortic origin of coronary arteries can be achieved with excellent results in pediatric patients, but concerns remain about the durability of surgery.
我们对文献进行了系统回顾和荟萃分析，以评估儿童和年轻成年人（<30 岁）异常冠状动脉起源的手术治疗结果。选择了 13 篇出版物，共包括 384 例患者。92%（95%CI：81%-98%）的病例采用了内膜段开窗术，汇总的早期和晚期死亡率分别为 0%（95%CI：0%-0.3%）和 0.1%（95%CI：0%-1%）。主动脉瓣反流的再次手术是偶发的。冠状动脉异常起源的外科治疗在儿科患者中可以取得极好的效果，但对手术的耐久性仍存在担忧。
