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瑞士接受腹主动脉瘤治疗患者的医院发病率和死亡率 - 瑞士 DRG 统计数据的二次分析。

Hospital incidence and mortality of patients treated for abdominal aortic aneurysms in Switzerland - a secondary analysis of Swiss DRG statistics data.

机构信息

Department for Vascular Surgery, University Hospital Zurich, Switzerland.

Department of Biostatistics and Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Switzerland.

出版信息

Swiss Med Wkly. 2022 Jun 27;152:w30191. doi: 10.4414/smw.2022.w30191. eCollection 2022 Jun 20.

Abstract

AIM OF THE STUDY

To analyse hospital incidence and in-hospital mortality of patients treated for abdominal aortic aneurysms in Switzerland.

METHODS

Secondary data analysis of case-related hospital discharge data of the Swiss Federal Statistical Office for the years 2009-2018. Patients who were hospitalised and surgically treated for nonruptured abdominal aortic aneurysms or hospitalised and treated for ruptured abdominal aortic aneurysms were included in the analysis. Standardised annual incidences rates were calculated using the European standard population 2013. In-hospital all-cause mortality rates were calculated as raw values and standardised for age, sex, and the van Walraven comorbidity score.

RESULTS

A total of 10,728 cases were included in this study, of which 87.1% were male. Overall, 22.7% of the patients presented with a ruptured abdominal aortic aneurysm; 46% of these cases were surgically treated whereas 54% received conservative therapy. The age-standardised cumulative hospital incidences for treatment of nonruptured abdominal aortic aneurysms were 2.6 (95% confidence interval 2.5-2.8) and 19.7 (19.2-20.1) per 100,000 for women and men, respectively; for ruptured aneurysms it was 0.4 (0.3-2.4) per 100,000 in women, and 2.7 (2.6-2.9) in men. The annual incidence rates were stable in the decade observed. The adjusted mortality rates for treatment of nonruptured aneurysms decreased from 5.5% (2.6-11.2%) in 2009 to 1.4% (0.5-3.6%) in 2018 in women, and from 2.4% (1.3-4.5%) in 2009 to 0.6% (0.2-1.5%) in 2018 in men. The adjusted mortality rates for treatment of ruptured abdominal aortic aneurysms remained high without relevant improvements for either sex over time: for women 32.4% (24.1-42.1%), for men 19.7% (16.8-22.8%).

CONCLUSIONS

The hospital incidence rates for nonruptured and ruptured abdominal aortic aneurysms remained unchanged in the decade observed. Compared with Germany, there was no evidence for a decrease in the annual incidence rates for ruptured abdominal aortic aneurysms in Switzerland. Mortality rates in the elective setting were low and decreased in the last decade but remained high in patients treated for ruptured aneurysms. Efforts to reduce the incidence of ruptured abdominal aortic aneurysms are needed to reduce aneurysm-related mortality in Switzerland.

摘要

研究目的

分析在瑞士接受治疗的腹主动脉瘤患者的住院发病率和院内死亡率。

方法

对瑞士联邦统计局 2009-2018 年与病例相关的住院数据进行二次数据分析。分析纳入了非破裂性腹主动脉瘤住院并接受手术治疗或破裂性腹主动脉瘤住院并接受治疗的患者。使用 2013 年欧洲标准人口计算标准化年度发病率。计算全因院内死亡率的原始值,并按年龄、性别和 van Walraven 合并症评分进行标准化。

结果

本研究共纳入 10728 例患者,其中 87.1%为男性。总体而言,22.7%的患者出现破裂性腹主动脉瘤;其中 46%的病例接受了手术治疗,54%接受了保守治疗。非破裂性腹主动脉瘤治疗的年龄标准化累积住院发病率分别为女性 2.6(95%置信区间 2.5-2.8)和 19.7(19.2-20.1)/10 万,破裂性动脉瘤为女性 0.4(0.3-2.4)/10 万,男性 2.7(2.6-2.9)/10 万。在观察的十年中,年度发病率保持稳定。非破裂性动脉瘤治疗的调整死亡率从 2009 年的 5.5%(2.6-11.2%)下降到 2018 年的女性 1.4%(0.5-3.6%),从 2009 年的男性 2.4%(1.3-4.5%)下降到 2018 年的 0.6%(0.2-1.5%)。随着时间的推移,破裂性腹主动脉瘤治疗的调整死亡率保持高位,无论性别均无明显改善:女性为 32.4%(24.1-42.1%),男性为 19.7%(16.8-22.8%)。

结论

在观察的十年中,非破裂性和破裂性腹主动脉瘤的住院发病率保持不变。与德国相比,瑞士破裂性腹主动脉瘤的年度发病率没有下降的证据。择期治疗的死亡率较低,在过去十年中有所下降,但破裂性动脉瘤治疗的死亡率仍然较高。需要努力降低破裂性腹主动脉瘤的发病率,以降低瑞士与动脉瘤相关的死亡率。

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