Mustafa A I, Ali B H, Hassan T
Reprod Nutr Dev (1980). 1987;27(1A):89-94. doi: 10.1051/rnd:19870109.
Furazolidone was given to male Nubian goats for 5 days at a therapeutic dose of 10 mg/kg or at a dose of 40 mg/kg, and the effect on semen morphology and biochemistry was studied. At the lower dose, furazolidone significantly reduced seminal ejaculate volume, the number of motile spermatozoa per ejaculate and the number of live spermatozoa per ejaculate, while secondary abnormalities increased. At a dose of 40 mg/kg, the same effects were produced and there were significant reductions in wave motion, percentage of motile spermatozoa and percentage of live spermatozoa. Fructose concentration was significantly reduced with both the doses, while citric acid was not affected by either one. Alkaline phosphatase activity was lower with 10 mg/kg of furazolidone and increased when the larger dose was administered.
将呋喃唑酮以10毫克/千克的治疗剂量或40毫克/千克的剂量给予雄性努比亚山羊，持续5天，并研究其对精液形态和生化指标的影响。在较低剂量下，呋喃唑酮显著降低了射精量、每次射精中活动精子的数量和每次射精中活精子的数量，而继发性异常情况增加。在40毫克/千克的剂量下，产生了相同的效果，且精子的波动、活动精子百分比和活精子百分比均显著降低。两种剂量均使果糖浓度显著降低，而柠檬酸不受任何一种剂量的影响。10毫克/千克的呋喃唑酮使碱性磷酸酶活性降低，而给予较大剂量时碱性磷酸酶活性增加。
