Mustafa A I, Ali B H, Hassan T
Vet Q. 1986 Oct;8(4):295-300. doi: 10.1080/01652176.1986.9694058.
Furazolidone (FZ) administered to goats orally at the recommended therapeutic dose (10 mg/kg body weight for 5 days) resulted in significant decreases in heart rate, pulse rate, and rectal temperature. No change was observed in respiratory rate or body weight, although a tendency towards a decrease in the latter was observed. An increase in the number of the erythrocytes was found. FZ also produced significant decreases in the pseudocholinesterase activity and plasma concentrations of total protein and ascorbic acid. A significant increase in the adrenal cholesterol concentration was observed while the weight of adrenal glands and their ascorbic acid concentration and content were unaffected. No significant histopathological changes were observed in treated goats.
以推荐治疗剂量(10毫克/千克体重,持续5天)口服给予山羊呋喃唑酮(FZ)后,心率、脉搏率和直肠温度显著下降。呼吸频率或体重未观察到变化,尽管观察到体重有下降趋势。发现红细胞数量增加。FZ还使假性胆碱酯酶活性以及总蛋白和抗坏血酸的血浆浓度显著降低。观察到肾上腺胆固醇浓度显著增加,而肾上腺重量及其抗坏血酸浓度和含量未受影响。在接受治疗的山羊中未观察到明显的组织病理学变化。