Key Laboratory of Brain, Cognition and Education Sciences, Ministry of Education, 55 Zhongshan Avenue West, Tianhe District, Guangzhou, 510631, China.
School of Psychology, South China Normal University, Guangzhou, 510631, China.
World J Pediatr. 2022 Dec;18(12):804-809. doi: 10.1007/s12519-022-00572-y. Epub 2022 Jun 27.
Developmental dyslexia (DD) is a specific impairment during the acquisition of reading skills and may have a lifelong negative impact on individuals. Reliable estimates of the prevalence of DD serve as the basis for evidence-based health resource allocation and policy making. However, the prevalence of DD in primary school children varies largely across studies. Moreover, it is unclear whether there are differences in prevalence in different genders and writing systems. Hence, the present study aims to conduct a systematic review and meta-analysis to assess the global prevalence of DD and to explore related factors.
We will undertake a comprehensive literature search in 14 databases, including EMBASE, PubMed, Web of Science, China National Knowledge Infrastructure and Cochrane, from their inception to June 2021. Cross-sectional and longitudinal studies that describe the prevalence of DD will be eligible. The quality of the included observational studies will be assessed using the Strengthening the Reporting of Observational Studies in Epidemiology statement. The risk of bias will be determined by sensitivity analysis to identify publication bias.
One meta-analysis will be conducted to estimate the prevalence of DD in primary school children. Heterogeneity will be assessed in terms of the properties of subjects (e.g., gender, grade and writing system) and method of diagnosis in the included primary studies. Subgroup analyses will also be performed for population and secondary outcomes.
The results will synthesize the prevalence of DD and provide information for policy-makers and public health specialists.
发育性阅读障碍（DD）是在阅读技能习得过程中出现的一种特定障碍，可能会对个体产生终身的负面影响。可靠的 DD 患病率估计值是基于循证的卫生资源分配和政策制定的基础。然而，不同研究中儿童发育性阅读障碍的患病率差异很大。此外，不同性别和书写系统的患病率是否存在差异尚不清楚。因此，本研究旨在进行系统综述和荟萃分析，以评估 DD 的全球患病率，并探讨相关因素。
我们将从数据库成立到 2021 年 6 月，对 14 个数据库（包括 EMBASE、PubMed、Web of Science、中国国家知识基础设施和 Cochrane）进行全面的文献检索。将纳入描述 DD 患病率的横断面和纵向研究。使用《观察性研究的报告质量评估工具》（Strengthening the Reporting of Observational Studies in Epidemiology statement）评估纳入的观察性研究的质量。通过敏感性分析确定偏倚风险，以识别发表偏倚。
将进行一项荟萃分析，以估计小学生 DD 的患病率。将根据纳入的初级研究中受试者的属性（如性别、年级和书写系统）和诊断方法来评估异质性。还将针对人群和次要结局进行亚组分析。
研究结果将综合 DD 的患病率，并为决策者和公共卫生专家提供信息。
