Institute of Research and Development, Duy Tan University, Da Nang, Viet Nam.
Immun Inflamm Dis. 2022 Jul;10(7):e661. doi: 10.1002/iid3.661.
Years of life lost (YLL) is a preferable indicator to assess the mortality impact of COVID-19. This indicator still has limits, however. Therefore, a new approach and its early-death weeks (eDW) index has been recently proposed to alter YLL. This study aims to add a new approach, the moving excess-deficit mortality model, and its method, the weeks of life lost (WLL) index. The new method was then used to measure WLL associated with COVID-19 in the United States (US).
The natural mortality law and the random pattern of spreading COVID-19 were employed to support calculating WLL. The natural mortality law implied that under the same living conditions and the weaker would die earlier. The random spreading of COVID-19 assumed that COVID-19 causes the weekly number of early deaths in equal proportions from all of those who would have died eventually distributed through the pandemic.
From Week 02 of 2020 to Week 44 of 2021, we found that the US population has lost 56,270,300 weeks to COVID-19; the average WLL per COVID-19-related death is 74 or 1.4 in the unit of years.
The results do not depend on the high heterogeneity of deaths (e.g., age, gender, health status) and on whether COVID-19 is the main cause of death. The moving excess-deficit mortality model and WLL index can be applied promptly at any time and anywhere once excess deaths occurred during the pandemic. The index also provides critical insights into COVID-19, which can support making public health policies and decisions.
寿命损失年(Years of life lost,YLL)是评估 COVID-19 死亡率影响的一个较好指标。然而,该指标仍存在局限性。因此,最近提出了一种新方法及其早期死亡周(early-death weeks,eDW)指数来改变 YLL。本研究旨在引入一种新方法,即移动超额亏损死亡率模型及其方法,即生命损失周(weeks of life lost,WLL)指数。然后,该新方法被用于测量与 COVID-19 相关的美国(United States,US)的 WLL。
采用自然死亡率规律和 COVID-19 随机传播模式来支持计算 WLL。自然死亡率规律意味着在相同的生活条件下,较弱的人会更早死亡。COVID-19 的随机传播假设 COVID-19 会导致每周因 COVID-19 而提前死亡的人数按比例来自所有最终因大流行而死亡的人。
从 2020 年第 02 周至 2021 年第 44 周,我们发现美国人口因 COVID-19 而损失了 56,270,300 周;每例与 COVID-19 相关的死亡的平均 WLL 为 74 周或 1.4 年。
结果不依赖于死亡的高度异质性(例如,年龄、性别、健康状况)以及 COVID-19 是否为主要死因。一旦大流行期间发生超额死亡,移动超额亏损死亡率模型和 WLL 指数可随时迅速应用。该指数还为 COVID-19 提供了关键见解,可支持制定公共卫生政策和决策。