Zhihui Kuang, Min Dai
Department of Orthopedics, The First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center of Jiangxi Province, Nanchang 330006, China.
ACS Biomater Sci Eng. 2022 Jul 11;8(7):2849-2857. doi: 10.1021/acsbiomaterials.2c00396. Epub 2022 Jun 27.
As an important derivative of graphene-based materials, graphene oxide (GO) not only plays an important role not only in optoelectronics and sensing but also in biology due to its unique mechanical, electronic, and optical properties. This article reviews the application of GO-based hydrogels in bone tissue engineering. Whether it is a hydrogel synthesized with natural polymer compounds, synthetic polymer chemicals, bioceramics, bioactive factors, or other materials, the addition of GO can significantly improve various properties of the hydrogel. We also introduce some high-performance GO-based hydrogels in this paper, proposing some insights into materials that may be applied to bone tissue engineering in the future.
作为石墨烯基材料的一种重要衍生物,氧化石墨烯(GO)不仅因其独特的机械、电子和光学性能在光电子学和传感领域发挥着重要作用,还在生物学领域具有重要意义。本文综述了氧化石墨烯基水凝胶在骨组织工程中的应用。无论是与天然高分子化合物、合成高分子化学品、生物陶瓷、生物活性因子或其他材料合成的水凝胶,添加氧化石墨烯都能显著改善水凝胶的各种性能。我们还在本文中介绍了一些高性能的氧化石墨烯基水凝胶,对未来可能应用于骨组织工程的材料提出了一些见解。