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一期单侧后路有限减压与双侧椎板切除病灶清除植骨融合内固定术治疗单节段老年脊柱结核的对比研究。

A comparative study of one-stage posterior unilateral limited laminectomy vs. bilateral laminectomy debridement and bone grafting fusion combined with internal fixation for the treatment of aged patients with single-segment spinal tuberculosis.

机构信息

Department of Spine Surgery and Orthopaedics, Xiangya Hospital, Central South University, Changsha, 410008, China.

Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Changsha, 410008, China.

出版信息

BMC Musculoskelet Disord. 2022 Jun 28;23(1):619. doi: 10.1186/s12891-022-05562-9.

DOI:10.1186/s12891-022-05562-9
PMID:35761205
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9238245/
Abstract

STUDY DESIGN

This is a retrospective study.

BACKGROUND

To assess and compare the clinical outcomes of posterior unilateral limited laminectomy (ULL) or bilateral laminectomy (BL) debridement and bone grafting fusion combined with internal fixation among aged patients with single-segment thoracic and lumbar tuberculosis (SST/LTB).

MATERIALS AND METHODS

We performed a retrospective study on aged patients (age > 65 years old) with SST/LTB from January 2010 to October 2018. We reviewed 36 aged patients who were treated with BL and 31 aged patients treated with ULL. All participants had undergone and finished a three-year follow-up. The outcomes were evaluated by the improvement of neurological function, correction Cobb angle, bone fusion time, and back pain, as well as operative time, blood loss, hospital stay, and postoperative complications.

RESULTS

The operative time, blood loss volume, and incidence of complications in group B were significantly less than those in group A (P < 0.01). The postoperative kyphotic angle in both groups was reduced significantly compared to the preoperative status (P < 0.01). The percentage of neurological improvement was 92.9% in group A and 90.9% in group B. All patients achieved solid bone fusion after surgery. At three-year follow-up, the angle loss in group B was significantly less than that in group A (P < 0.01); Furthermore, patients in group B had a lower average visual analog scale score of back pain and Oswestry Disability Index score than patients in group A (P < 0.05).

CONCLUSIONS

For aged patients with SST/LTB, ULL is a safer and more effective surgical treatment than BL.

摘要

研究设计

这是一项回顾性研究。

背景

评估和比较单侧后路有限减压(ULL)或双侧减压(BL)清创植骨融合内固定治疗老年单节段胸腰椎结核(SST/LTB)的临床疗效。

材料和方法

我们对 2010 年 1 月至 2018 年 10 月期间的老年 SST/LTB 患者(年龄>65 岁)进行了回顾性研究。回顾性分析 BL 治疗的 36 例老年患者和 ULL 治疗的 31 例老年患者。所有患者均完成了 3 年随访。通过神经功能改善、矫正 Cobb 角、骨融合时间和腰背疼痛,以及手术时间、出血量、住院时间和术后并发症来评估疗效。

结果

B 组的手术时间、出血量和并发症发生率明显低于 A 组(P<0.01)。两组术后后凸角均明显小于术前(P<0.01)。A 组神经功能改善率为 92.9%,B 组为 90.9%。所有患者术后均获得了坚固的骨融合。在 3 年随访时,B 组的角度丢失明显少于 A 组(P<0.01);此外,B 组患者的腰背疼痛平均视觉模拟评分和 Oswestry 功能障碍指数评分均低于 A 组(P<0.05)。

结论

对于老年 SST/LTB 患者,ULL 是一种比 BL 更安全、更有效的手术治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa51/9238245/0a7feed54ec0/12891_2022_5562_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa51/9238245/0c180f00151c/12891_2022_5562_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa51/9238245/9b09711f8622/12891_2022_5562_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa51/9238245/fd30951623dc/12891_2022_5562_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa51/9238245/7de8e3817e25/12891_2022_5562_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa51/9238245/0a7feed54ec0/12891_2022_5562_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa51/9238245/0c180f00151c/12891_2022_5562_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa51/9238245/9b09711f8622/12891_2022_5562_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa51/9238245/fd30951623dc/12891_2022_5562_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa51/9238245/7de8e3817e25/12891_2022_5562_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa51/9238245/0a7feed54ec0/12891_2022_5562_Fig5_HTML.jpg

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3
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J Orthop Surg Res. 2019 Jan 22;14(1):24. doi: 10.1186/s13018-019-1063-7.
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