Physical Therapy Post-Graduate Program and Physical Therapy Department, Brazil.
Study Group on Chronic Pain (NEDoC), Laboratory of Research on Electrophysical Agents (LAREF), Physical Therapy Department, Brazil.
Eur J Pain. 2022 Sep;26(8):1759-1767. doi: 10.1002/ejp.1999. Epub 2022 Jul 6.
Dysmenorrhoea is a prevalent pain condition that affects women of reproductive age, who are monthly exposed to this pain, usually until they reach adult age, or even after that, which can predispose them to Central Sensitization. The present study aimed to observe the association between menstrual characteristics and central sensitivity symptoms in women.
Cross-sectional study. Brazilian women (n = 10,402) answered an online form comprised of questions regarding their gynaecological history, the Numerical Rating Scale for pain and the Central Sensitization Inventory, part A. For the analysis, we separated women into two groups: the Central Sensitivity Symptoms group (n = 5200) and the no Central Sensitivity Symptoms group (n = 5202). We performed a binary logistic regression with the backward insertion method for the variables with p < 0.05 in the bivariate analysis between groups. The significance level was set at 5%.
Prevalence of dysmenorrhoea was 67.3%, and 32.2% of women in the Central Sensitivity Symptoms group reported pain >8 during their menstrual period. The logistic regression showed that greater levels of menstrual pain (odds ratio 1.12), gynaecological diseases (odds ratio 1.51), presence of dysmenorrhoea since adolescence (odds ratio 1.20) and irregular menstrual cycles (odds ratio 1.47) increased the likelihood of women presenting with Central Sensitivity Symptoms (p < 0.05 for all comparisons).
The present study shows that Central Sensitivity Symptoms are present in about 50% of women and are associated with menstrual characteristics such as dysmenorrhoea-related pain intensity, cycle regularity, presence of dysmenorrhoea since adolescence accompanied by gynaecological diseases.
Central sensitivity symptoms occur in 50% of women and are more present in women with dysmenorrhoea. They are associated with cycle regularity, presence of dysmenorrhoea since adolescence and gynaecological diseases.
Women that suffer from dysmenorrhoea and are of higher socio-economic and educational levels may have been more propense to respond to the invitation; as such, the findings of the present study should be carefully interpreted.
痛经是一种常见的疼痛状况，影响育龄妇女，她们每月都会经历这种疼痛，通常要到成年甚至成年后才能缓解，这可能导致中枢敏化。本研究旨在观察女性月经特征与中枢敏感症状之间的关系。
横断面研究。巴西女性（n=10402）在线回答了一个包含妇科病史、疼痛数字评分量表和中枢敏感症状量表 A 部分的问卷。为了分析，我们将女性分为两组：中枢敏感症状组（n=5200）和无中枢敏感症状组（n=5202）。我们对组间双变量分析中 p<0.05 的变量进行了向后插入的二元逻辑回归。显著性水平设为 5%。
痛经的患病率为 67.3%，中枢敏感症状组中 32.2%的女性报告在月经期间疼痛>8。逻辑回归显示，月经疼痛程度较高（比值比 1.12）、妇科疾病（比值比 1.51）、青春期开始痛经（比值比 1.20）和月经周期不规则（比值比 1.47）会增加女性出现中枢敏感症状的可能性（所有比较的 p<0.05）。
本研究表明，中枢敏感症状在约 50%的女性中存在，与月经特征相关，如痛经相关的疼痛强度、周期规律、青春期开始痛经伴妇科疾病。
中枢敏感症状在 50%的女性中出现，在痛经患者中更为常见。它们与周期规律、青春期开始痛经和妇科疾病有关。
患有痛经且社会经济和教育水平较高的女性可能更倾向于回应邀请；因此，应谨慎解释本研究的结果。
