Matsusaka Municipal Hospital, Respiratory Center, Matsusaka, Japan.
Department of Radiation Oncology, Japanese Red Cross Ise Hospital, Ise, Japan.
Thorac Cancer. 2022 Aug;13(15):2267-2270. doi: 10.1111/1759-7714.14551. Epub 2022 Jun 27.
The abscopal effect without concomitant immunotherapy is a rare event, including among cases of lung cancer. Furthermore, the occurrence of limited abscopal effect for only a single lesion in the metastatic organ consistent with the irradiated organ would be an even more rare event. A 94-year-old man was diagnosed with advanced lung cancer with osteolytic bone metastases in his right iliac bone, and the right side of his axial vertebrae. After palliative radiation therapy to the right iliac lesion for pain relief without other anticancer therapy, the axial vertebral osteolytic lesion disappeared despite no reduction in the other lesions. This case furthers our understanding of the pathogenesis of the abscopal effect.
在没有伴随免疫疗法的情况下，远隔效应是一种罕见的事件，包括肺癌病例。此外，转移性器官中仅单个病变出现有限的远隔效应，且与受照器官一致，这将是更为罕见的事件。一名 94 岁男性被诊断患有晚期肺癌，其右侧髂骨和轴向椎体有溶骨性骨转移。在对右侧髂骨病变进行姑息性放疗以缓解疼痛而未进行其他抗癌治疗后，尽管其他病变没有减少，但轴向椎体溶骨性病变消失了。该病例进一步加深了我们对远隔效应发病机制的理解。
