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爱泼斯坦-巴尔病毒的口眼传播感染。在新冠病毒2019大流行时代,戴口罩可能成为一种新的传播途径。

Oral-ocular trans infection of Epstein Barr virus. A possible new way of transmission by wearing masks in the SARS-CoV-2 era.

作者信息

Peiretti Enrico, Demarinis Giuseppe, Casu Cinzia, Scano Alessandra, Orrù Germano

机构信息

Eye Clinic, Department of Surgical Science, University of Cagliari, Cagliari, Italy.

International PhD in Innovation Sciences and Technologies (IST), University of Cagliari, Italy.

出版信息

Am J Ophthalmol Case Rep. 2022 Sep;27:101626. doi: 10.1016/j.ajoc.2022.101626. Epub 2022 Jun 22.

Abstract

PURPOSE

To describe a case of an infective vitreitis with an exudative retinal detachment in a 56-year-old lady who was previously affected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

OBSERVATIONS

A broad workup for infections including the main viruses and bacteria was performed. Salivary droplets, tear film and vitreous samples were collected, resulting positive only for Epstein-Barr virus (EBV). Viraemia and immunoglobulin M for EBV negative, whereas immunoglobulin G positive. The patient showed a simultaneous painless erosion on the right margin of the tongue that's with the lab swab demonstrated the presence of EBV at the same time the vitreitis in the left eye was present.

CONCLUSIONS AND IMPORTANCE

Our speculation is that a continuous use of the mask, especially in immunocompromised subjects, it might create a new route for spreading infectious oral agents in the ocular area, and this case is a warning for all the ophthalmologists that have to be aware of this threatening possibility in the COVID era.

摘要

目的

描述一例56岁女性感染性玻璃体炎伴渗出性视网膜脱离的病例,该女性曾感染严重急性呼吸综合征冠状病毒2(SARS-CoV-2)。

观察结果

对包括主要病毒和细菌在内的感染进行了全面检查。收集了唾液飞沫、泪膜和玻璃体样本,结果仅爱泼斯坦-巴尔病毒(EBV)呈阳性。EBV病毒血症和免疫球蛋白M为阴性,而免疫球蛋白G为阳性。患者舌右侧边缘同时出现无痛性糜烂,实验室拭子检测显示存在EBV,与此同时左眼出现玻璃体炎。

结论与重要性

我们推测,持续佩戴口罩,尤其是在免疫功能低下的人群中,可能会为传染性口腔病原体在眼部区域传播创造一条新途径,该病例为所有眼科医生敲响了警钟,他们必须意识到在新冠疫情时代存在这种潜在威胁。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e39f/9249590/93df0ab2b5a6/gr1.jpg

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