Biomedical Imaging Research Institute, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Department of Cardiovascular, Lanzhou University Second Hospital, Lanzhou, China.
Ther Adv Cardiovasc Dis. 2022 Jan-Dec;16:17539447221107737. doi: 10.1177/17539447221107737.
Intracardiac thrombus in the left atrium and atrial appendage (LA/LAA) and left ventricle (LV) increases the risk of systemic thromboembolism and causes potentially devastating diseases such as ischemic stroke and acute ischemia in abdominal organs and lower extremities. Detecting the presence and monitoring the resolution of left heart intracardiac thrombus are of vital importance for stratifying patients and guiding treatment decisions. Currently, echocardiography is the most frequently used method for the above clinical needs, followed by computed tomography. An increasing number of studies have been performed to investigate the value of cardiac magnetic resonance (CMR) as an alternative imaging modality given its several unique strengths. This article provides an overview of the clinical relevance of the LA/LAA and LV thrombus as well as the diagnostic performance of the current imaging modalities and emerging CMR techniques.
左心房和左心耳(LA/LAA)及左心室(LV)内的心腔内血栓会增加全身性血栓栓塞的风险,并导致潜在的破坏性疾病,如缺血性中风以及腹部器官和下肢的急性缺血。检测左心室内心腔内血栓的存在并监测其溶解情况对于分层患者和指导治疗决策至关重要。目前,超声心动图是满足上述临床需求最常使用的方法,其次是计算机断层扫描。越来越多的研究已经开展,以探讨心脏磁共振(CMR)作为替代成像方式的价值,因为其具有多种独特的优势。本文综述了 LA/LAA 和 LV 血栓的临床相关性以及当前成像方式和新兴 CMR 技术的诊断性能。