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自身免疫性疾病相关溃疡的临床特征及诊治研究进展

[Research advances on the clinical characteristics and diagnosis and treatment of autoimmune disease-related ulcers].

作者信息

Zhao L, Su K S, Ye Z, Jiang Z Y, Chen L, Long Y

机构信息

Department of Rheumatology, the First Hospital of Jilin University, Changchun 130021, China.

出版信息

Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi. 2022 Jun 20;38(6):558-562. doi: 10.3760/cma.j.cn501120-20211019-00358.

Abstract

Studies have shown that autoimmune disease (AID)-related ulcers are disease complications that lead to serious poor prognosis such as infection and disability. It is difficult to make a clear diagnosis and there are contradictions between the applications of immunosuppressive therapy and anti-infectious therapy. Improper diagnosis and immunosuppressive therapy can easily delay the timing of anti-infectious therapy and surgery for patients, which bring adverse effects on the prognosis of patients. This paper reviews the concept, clinical characteristics and treatment suggestions of each subtype of AID-related ulcers, in order to provide more ideas for AID-related ulcers' clinical diagnosis and treatment.

摘要

研究表明,自身免疫性疾病(AID)相关溃疡是导致感染和残疾等严重不良预后的疾病并发症。明确诊断困难,免疫抑制治疗与抗感染治疗的应用存在矛盾。诊断不当和免疫抑制治疗容易延误患者抗感染治疗和手术时机,给患者预后带来不利影响。本文综述了AID相关溃疡各亚型的概念、临床特点及治疗建议,以期为AID相关溃疡的临床诊治提供更多思路。

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