间充质干细胞及其衍生物治疗痤疮瘢痕的研究进展
[Research advances on mesenchymal stem cells and their derivatives in the treatment of acne scars].
作者信息
Li F, Cai Y, Deng C L
机构信息
Department of Dermatology, the Affiliated Hospital of Zunyi Medical University, Zunyi 563003, China.
Department of Burns and Plastic Surgery, the Affiliated Hospital of Zunyi Medical University, Zunyi 563003, China.
出版信息
Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi. 2022 Jun 20;38(6):595-600. doi: 10.3760/cma.j.cn501120-20210510-00177.
Acne is a common chronic inflammatory disease of the skin that often occurs on the face, and acne scars are often secondary to the healing process of acne, which often leads to impaired appearance and psychological disorders of patients. The current treatment for acne scars is extremely difficult. With the development of regenerative medicine, stem cell transplantation has become a new treatment for acne scars. In recent years, it has been reported that stem cells and their derivatives can effectively antagonize the formation of acne scars. Therefore, this paper briefly reviews the basic and clinical researches on the treatment of acne scars with various mesenchymal stem cells and their derivatives, aiming to provide theoretical basis and reference for the stem cell therapy of acne scars.
痤疮是一种常见的慢性皮肤炎症性疾病，常发生于面部，而痤疮瘢痕往往继发于痤疮的愈合过程，这常常导致患者外观受损和心理障碍。目前针对痤疮瘢痕的治疗极其困难。随着再生医学的发展，干细胞移植已成为治疗痤疮瘢痕的一种新方法。近年来，有报道称干细胞及其衍生物可有效对抗痤疮瘢痕的形成。因此，本文简要综述了各种间充质干细胞及其衍生物治疗痤疮瘢痕的基础研究和临床研究，旨在为痤疮瘢痕的干细胞治疗提供理论依据和参考。
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