• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
[Research advances on mesenchymal stem cells and their derivatives in the treatment of acne scars].间充质干细胞及其衍生物治疗痤疮瘢痕的研究进展
Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi. 2022 Jun 20;38(6):595-600. doi: 10.3760/cma.j.cn501120-20210510-00177.
2
Laser punch-out for acne scars.痤疮疤痕的激光打孔术
Aesthetic Plast Surg. 2001 Jan-Feb;25(1):46-51. doi: 10.1007/s002660010094.
3
Nanofat and Platelet-Rich Plasma injections used in a case of severe acne scars.纳米脂肪和富血小板血浆注射治疗严重痤疮瘢痕。
J Stomatol Oral Maxillofac Surg. 2022 Oct;123(5):572-575. doi: 10.1016/j.jormas.2022.04.018. Epub 2022 Apr 26.
4
Prospective Study of Pathogenesis of Atrophic Acne Scars and Role of Macular Erythema.萎缩性痤疮瘢痕发病机制及黄斑红斑作用的前瞻性研究
J Drugs Dermatol. 2017 Jun 1;16(6):566-572.
5
Study of interleukin-1 beta expression in acne vulgaris and acne scars.寻常痤疮和痤疮瘢痕中白细胞介素-1β表达的研究。
J Cosmet Dermatol. 2022 Oct;21(10):4864-4870. doi: 10.1111/jocd.14852. Epub 2022 May 23.
6
Evaluation of autologous adipose-derived stem cells vs. fractional carbon dioxide laser in the treatment of post acne scars: a split-face study.自体脂肪来源干细胞与二氧化碳点阵激光治疗痤疮后瘢痕的疗效比较:一项随机自身对照研究。
Int J Dermatol. 2019 Oct;58(10):1212-1222. doi: 10.1111/ijd.14567. Epub 2019 Jul 11.
7
Prevention and Reduction of Atrophic Acne Scars with Adapalene 0.3%/Benzoyl Peroxide 2.5% Gel in Subjects with Moderate or Severe Facial Acne: Results of a 6-Month Randomized, Vehicle-Controlled Trial Using Intra-Individual Comparison.阿达帕林 0.3%/过氧化苯甲酰 2.5%凝胶预防和减少中重度痤疮患者的萎缩性痤疮瘢痕:一项使用个体内对照的 6 月随机、对照临床试验结果。
Am J Clin Dermatol. 2018 Apr;19(2):275-286. doi: 10.1007/s40257-018-0352-y.
8
Improvement of Atrophic Acne Scars in Skin of Color Using Topical Synthetic Epidermal Growth Factor (EGF) Serum: A Pilot Study.使用外用合成表皮生长因子(EGF)血清改善有色人种皮肤萎缩性痤疮瘢痕:一项初步研究。
J Drugs Dermatol. 2017 Apr 1;16(4):322-326.
9
Interventions for acne scars.痤疮瘢痕的干预措施。
Cochrane Database Syst Rev. 2016 Apr 3;4(4):CD011946. doi: 10.1002/14651858.CD011946.pub2.
10
Treatment of atrophic facial acne scars with the Er:YAG laser: a Turkish experience.铒激光治疗面部萎缩性痤疮瘢痕:土耳其的经验
J Cosmet Laser Ther. 2010 Apr;12(2):65-72. doi: 10.3109/14764171003706141.

本文引用的文献

1
Application of ADSCs and their Exosomes in Scar Prevention.脂肪来源干细胞及其外泌体在瘢痕预防中的应用。
Stem Cell Rev Rep. 2022 Mar;18(3):952-967. doi: 10.1007/s12015-021-10252-5. Epub 2021 Sep 12.
2
SDF Factor-1α Promotes the Migration, Proliferation, and Osteogenic Differentiation of Mouse Bone Marrow Mesenchymal Stem Cells Through the Wnt/β-Catenin Pathway.SDF-1α 通过 Wnt/β-连环蛋白通路促进小鼠骨髓间充质干细胞的迁移、增殖和成骨分化。
Stem Cells Dev. 2021 Jan 15;30(2):106-117. doi: 10.1089/scd.2020.0165. Epub 2020 Dec 17.
3
Combination Treatment with Human Adipose Tissue Stem Cell-derived Exosomes and Fractional CO2 Laser for Acne Scars: A 12-week Prospective, Double-blind, Randomized, Split-face Study.人脂肪组织干细胞衍生外泌体与二氧化碳点阵激光联合治疗痤疮瘢痕:一项为期12周的前瞻性、双盲、随机、半脸对照研究。
Acta Derm Venereol. 2020 Nov 4;100(18):adv00310. doi: 10.2340/00015555-3666.
4
Therapeutic applications of adipose cell-free derivatives: a review.脂肪细胞无细胞衍生物的治疗应用:综述。
Stem Cell Res Ther. 2020 Jul 22;11(1):312. doi: 10.1186/s13287-020-01831-3.
5
Hepatocyte Growth Factor Secreted from Human Adipose-Derived Stem Cells Inhibits Fibrosis in Hypertrophic Scar Fibroblasts.人脂肪来源干细胞分泌的肝细胞生长因子抑制增生性瘢痕成纤维细胞的纤维化。
Curr Mol Med. 2020;20(7):558-571. doi: 10.2174/1566524020666200106095745.
6
Bone marrow concentrate-induced mesenchymal stem cell conditioned medium facilitates wound healing and prevents hypertrophic scar formation in a rabbit ear model.骨髓浓缩物诱导间充质干细胞条件培养基促进兔耳模型创面愈合,防止增生性瘢痕形成。
Stem Cell Res Ther. 2019 Aug 28;10(1):275. doi: 10.1186/s13287-019-1383-x.
7
The Treatment of Acne Scars, a 30-Year Journey.痤疮瘢痕的治疗:30 年的探索历程。
Am J Clin Dermatol. 2019 Oct;20(5):683-690. doi: 10.1007/s40257-019-00451-9.
8
Evaluation of autologous adipose-derived stem cells vs. fractional carbon dioxide laser in the treatment of post acne scars: a split-face study.自体脂肪来源干细胞与二氧化碳点阵激光治疗痤疮后瘢痕的疗效比较:一项随机自身对照研究。
Int J Dermatol. 2019 Oct;58(10):1212-1222. doi: 10.1111/ijd.14567. Epub 2019 Jul 11.
9
Efficacy of stem cell-conditioned medium platelet-rich plasma as an adjuvant to ablative fractional CO laser resurfacing for atrophic post-acne scars: a split-face clinical trial.干细胞条件培养基联合富血小板血浆作为剥脱性分数二氧化碳激光换肤治疗萎缩性痤疮瘢痕辅助治疗的疗效:一项半脸临床试验。
J Dermatolog Treat. 2021 Mar;32(2):242-249. doi: 10.1080/09546634.2019.1630701. Epub 2019 Jul 5.
10
Objective analysis of volume restoration in atrophic acne scars and skin pores: a split study using human stem cell-conditioned media.目的分析萎缩性痤疮瘢痕和皮肤毛孔的体积恢复:使用人干细胞条件培养基的分割研究。
J Dermatolog Treat. 2021 Feb;32(1):73-77. doi: 10.1080/09546634.2019.1628915. Epub 2019 Jul 5.

间充质干细胞及其衍生物治疗痤疮瘢痕的研究进展

[Research advances on mesenchymal stem cells and their derivatives in the treatment of acne scars].

作者信息

Li F, Cai Y, Deng C L

机构信息

Department of Dermatology, the Affiliated Hospital of Zunyi Medical University, Zunyi 563003, China.

Department of Burns and Plastic Surgery, the Affiliated Hospital of Zunyi Medical University, Zunyi 563003, China.

出版信息

Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi. 2022 Jun 20;38(6):595-600. doi: 10.3760/cma.j.cn501120-20210510-00177.

DOI:10.3760/cma.j.cn501120-20210510-00177
PMID:35764589
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11705264/
Abstract

Acne is a common chronic inflammatory disease of the skin that often occurs on the face, and acne scars are often secondary to the healing process of acne, which often leads to impaired appearance and psychological disorders of patients. The current treatment for acne scars is extremely difficult. With the development of regenerative medicine, stem cell transplantation has become a new treatment for acne scars. In recent years, it has been reported that stem cells and their derivatives can effectively antagonize the formation of acne scars. Therefore, this paper briefly reviews the basic and clinical researches on the treatment of acne scars with various mesenchymal stem cells and their derivatives, aiming to provide theoretical basis and reference for the stem cell therapy of acne scars.

摘要

痤疮是一种常见的慢性皮肤炎症性疾病,常发生于面部,而痤疮瘢痕往往继发于痤疮的愈合过程,这常常导致患者外观受损和心理障碍。目前针对痤疮瘢痕的治疗极其困难。随着再生医学的发展,干细胞移植已成为治疗痤疮瘢痕的一种新方法。近年来,有报道称干细胞及其衍生物可有效对抗痤疮瘢痕的形成。因此,本文简要综述了各种间充质干细胞及其衍生物治疗痤疮瘢痕的基础研究和临床研究,旨在为痤疮瘢痕的干细胞治疗提供理论依据和参考。