Owari Go, Kono Kenichi, Nishida Yusuke
Department of Rehabilitation, Inzai General Hospital, Inzai City, Japan.
Department of Physical Therapy, International University of Health and Welfare, Narita City, Japan.
Prog Rehabil Med. 2022 Jun 7;7:20220029. doi: 10.2490/prm.20220029. eCollection 2022.
The purpose of this study was to determine the relationship between depression and heart rate variability (HRV) in rehabilitation ward inpatients.
Depression was assessed using the Self-Rating Depression Scale (SDS) in 10 inpatients in a convalescent rehabilitation ward. We also measured R-R intervals during nighttime rest, evaluated HRV by frequency analysis, and confirmed the association between autonomic activity and depression by calculation of Spearman's rank correlation coefficient.
A negative correlation was found between depression and the very low-frequency (VLF) band of HRV (ρ=-0.70, P<0.05). SDS showed no significant correlation with low-frequency (LF) band (ρ=-0.32, P=0.36) or high-frequency (HF) band (ρ=-0.21, P=0.46).
The results of this study suggest that the VLF band of HRV may be an effective indicator of autonomic activity in the evaluation of depression. Further studies are needed to verify the usefulness of the VLF band of HRV as an indicator for detecting depression.
本研究旨在确定康复病房住院患者抑郁与心率变异性（HRV）之间的关系。
使用自评抑郁量表（SDS）对某康复疗养病房的10名住院患者进行抑郁评估。我们还在夜间休息期间测量了R-R间期，通过频率分析评估HRV，并通过计算Spearman等级相关系数来确认自主神经活动与抑郁之间的关联。
发现抑郁与HRV的极低频（VLF）波段之间存在负相关（ρ=-0.70，P<0.05）。SDS与低频（LF）波段（ρ=-0.32，P=0.36）或高频（HF）波段（ρ=-0.21，P=0.46）均无显著相关性。
本研究结果表明，HRV的VLF波段可能是评估抑郁时自主神经活动的有效指标。需要进一步研究以验证HRV的VLF波段作为检测抑郁指标的有用性。
