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巴西马托格罗索州大库亚巴的宫颈癌特异性生存。

Cervical cancer specific survival in Grande Cuiabá, Mato Grosso State, Brazil.

机构信息

Universidade Federal de Mato Grosso, Foundation for Support and Development - Cuiabá (MT), Brazil.

Universidade Federal de Mato Grosso, Public Health Institute, Graduate Program - Cuiabá (MT), Brazil.

出版信息

Rev Bras Epidemiol. 2022 Jun 24;25(Supl 1):e220017. doi: 10.1590/1980-549720220017.supl.1. eCollection 2022.

Abstract

OBJECTIVE

To estimate specific five-year survival in women diagnosed with cervical cancer living in the municipalities of Cuiabá and Várzea Grande, in the state of Mato Grosso, Brazil.

METHODS

This is a retrospective cohort study with information from the Cuiabá Population-based Cancer Registry and the Mortality Information System. To estimate the probability of specific survival in five years, the Kaplan-Meier estimator and the log-rank test were used aiming at verifying if there were statistical differences in the lifetime per groups. To verify the proportionality of the failure rates, the Schoenfeld residual test was used according to the statistical significance level of 0.05.

RESULTS

Specific five-year survival and median time were 90.0% and 50.3 months, respectively, for cervical cancer. When analyzing by age, the highest specific survival was among women aged 20 to 49 years (91.7%) and median time was 53.3 months. For the histological type, the highest specific survival was among women with adenocarcinoma (92.3%) and the mean survival time was 53.5 months.

CONCLUSION

This study showed that specific survival after five years of diagnosis remained about 90% in patients with cervical cancer. Patients aged 20 to 49 years had higher specific survival and there was statistically significant difference only between age groups.

摘要

目的

评估巴西马托格罗索州库亚巴和瓦尔泽格兰德市诊断为宫颈癌的女性的五年具体生存率。

方法

这是一项回顾性队列研究,信息来自库亚巴基于人群的癌症登记处和死亡率信息系统。为了估计五年特定生存率的概率,使用了 Kaplan-Meier 估计器和对数秩检验,旨在验证组间生存期是否存在统计学差异。为了验证失败率的比例性,根据统计学意义水平 0.05 使用了 Schoenfeld 残差检验。

结果

宫颈癌的五年特定生存率和中位时间分别为 90.0%和 50.3 个月。按年龄分析时,20 至 49 岁女性的特定生存率最高(91.7%),中位时间为 53.3 个月。在组织学类型方面,腺癌患者的特定生存率最高(92.3%),平均生存时间为 53.5 个月。

结论

本研究表明,宫颈癌诊断五年后,特定生存率仍保持在 90%左右。20 至 49 岁的患者具有更高的特定生存率,且仅在年龄组之间存在统计学显著差异。

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