第三剂 mRNA COVID-19 疫苗接种后出现严重心肌炎：多模式治疗方法的应用。
Severe myopericarditis following the third dose of an mRNA COVID-19 vaccine: utility of a multimodal treatment approach.
机构信息
Medicine, University of Florida College of Medicine, Gainesville, Florida, USA
Internal Medicine, University of Florida College of Medicine, Gainesville, Florida, USA.
出版信息
BMJ Case Rep. 2022 Jun 29;15(6):e249533. doi: 10.1136/bcr-2022-249533.
Abstract
We report a rare case of severe myopericarditis in a healthy man in his 20s after the third dose of an mRNA COVID-19 vaccine. His symptoms and troponinemia resolved with a beta-blocker in addition to standard anti-inflammatory therapy, highlighting the utility of multimodal therapy.
摘要
我们报告了一例罕见的 20 多岁健康男性在接种第三剂 mRNA COVID-19 疫苗后发生严重心肌炎的病例。除了标准的抗炎治疗外，他的症状和肌钙蛋白血症通过β受体阻滞剂得到了缓解，这突出了多模式治疗的效用。
相似文献
1
Severe myopericarditis following the third dose of an mRNA COVID-19 vaccine: utility of a multimodal treatment approach.第三剂 mRNA COVID-19 疫苗接种后出现严重心肌炎：多模式治疗方法的应用。
BMJ Case Rep. 2022 Jun 29;15(6):e249533. doi: 10.1136/bcr-2022-249533.
2
Acute Myopericarditis Post-Intravenous Injection of Coronavirus Disease 2019 (COVID-19) mRNA Vaccine Differs From Viral Myocarditis.2019冠状病毒病（COVID-19）mRNA疫苗静脉注射后急性心肌心包炎与病毒性心肌炎不同。
Clin Infect Dis. 2022 Aug 24;75(1):e926. doi: 10.1093/cid/ciab980.
3
Risk of myopericarditis following COVID-19 mRNA vaccination in a large integrated health system: A comparison of completeness and timeliness of two methods.在大型综合医疗体系中，COVID-19 mRNA 疫苗接种后的心肌炎风险：两种方法的完整性和及时性比较。
Pharmacoepidemiol Drug Saf. 2022 Aug;31(8):921-925. doi: 10.1002/pds.5439. Epub 2022 Apr 16.
4
Cardiac complications following mRNA COVID-19 vaccines: A systematic review of case reports and case series.mRNA COVID-19 疫苗接种后的心脏并发症：病例报告和病例系列的系统评价。
Rev Med Virol. 2022 Jul;32(4):e2318. doi: 10.1002/rmv.2318. Epub 2021 Dec 17.
5
Use of mRNA COVID-19 Vaccine After Reports of Myocarditis Among Vaccine Recipients: Update from the Advisory Committee on Immunization Practices - United States, June 2021.mRNA COVID-19 疫苗接种后出现心肌炎报告：免疫实践咨询委员会更新-美国，2021 年 6 月。
MMWR Morb Mortal Wkly Rep. 2021 Jul 9;70(27):977-982. doi: 10.15585/mmwr.mm7027e2.
6
In-Depth Evaluation of a Case of Presumed Myocarditis After the Second Dose of COVID-19 mRNA Vaccine.第二剂 COVID-19 mRNA 疫苗接种后疑似心肌炎病例的深入评估。
Circulation. 2021 Aug 10;144(6):487-498. doi: 10.1161/CIRCULATIONAHA.121.056038. Epub 2021 Jun 16.
7
Myocarditis and/or pericarditis risk after mRNA COVID-19 vaccination: A Canadian head to head comparison of BNT162b2 and mRNA-1273 vaccines.mRNA COVID-19 疫苗接种后的心肌炎和/或心包炎风险：BNT162b2 和 mRNA-1273 疫苗的加拿大头对头比较。
Vaccine. 2022 Jul 30;40(32):4663-4671. doi: 10.1016/j.vaccine.2022.05.048. Epub 2022 May 25.
8
Incidence, Clinical Presentation, and Management of Myocarditis following mRNA-Based Covid-19 Vaccines: A Brief Report.mRNA 新冠病毒疫苗接种后心肌炎的发病率、临床表现和处理：简要报告。
Cardiology. 2022;147(4):406-412. doi: 10.1159/000522216. Epub 2022 Feb 1.
9
Reports of myocarditis and pericarditis following mRNA COVID-19 vaccination: a systematic review of spontaneously reported data from the UK, Europe and the USA and of the scientific literature.报告显示，接种 mRNA COVID-19 疫苗后可能引发心肌炎和心包炎：对来自英国、欧洲和美国的自发报告数据以及科学文献的系统评价。
BMJ Open. 2022 May 25;12(5):e059223. doi: 10.1136/bmjopen-2021-059223.
10
COVID-19 Vaccine-Related Myocardial and Pericardial Inflammation.COVID-19 疫苗相关的心肌和心包炎症。
Curr Cardiol Rep. 2022 Dec;24(12):2031-2041. doi: 10.1007/s11886-022-01801-6. Epub 2022 Nov 28.
引用本文的文献
1
A Young Male Presenting With Chest Pain, Elevated Troponin Levels, and a Clinical Dilemma: A Case Report.一名年轻男性因胸痛、肌钙蛋白水平升高及临床困境就诊：病例报告
Cureus. 2023 Dec 12;15(12):e50391. doi: 10.7759/cureus.50391. eCollection 2023 Dec.
2
Myocarditis and coronavirus disease 2019 vaccination: A systematic review and meta-summary of cases.心肌炎与 2019 年冠状病毒病疫苗接种：病例的系统评价和汇总分析。
Biomol Biomed. 2023 Jul 3;23(4):546-567. doi: 10.17305/bb.2022.8779.
本文引用的文献
1
Myocarditis after COVID-19 mRNA vaccination: clinical observations and potential mechanisms.新冠病毒 mRNA 疫苗接种后的心肌炎：临床观察及潜在机制。
Nat Rev Cardiol. 2022 Feb;19(2):75-77. doi: 10.1038/s41569-021-00662-w.
2
Myocarditis after Covid-19 Vaccination in a Large Health Care Organization.大型医疗机构中接种新冠疫苗后的心肌炎。
N Engl J Med. 2021 Dec 2;385(23):2132-2139. doi: 10.1056/NEJMoa2110737. Epub 2021 Oct 6.
3
Use of mRNA COVID-19 Vaccine After Reports of Myocarditis Among Vaccine Recipients: Update from the Advisory Committee on Immunization Practices - United States, June 2021.mRNA COVID-19 疫苗接种后出现心肌炎报告：免疫实践咨询委员会更新-美国，2021 年 6 月。
MMWR Morb Mortal Wkly Rep. 2021 Jul 9;70(27):977-982. doi: 10.15585/mmwr.mm7027e2.
4
Comparison of Original and 2018 Lake Louise Criteria for Diagnosis of Acute Myocarditis: Results of a Validation Cohort.急性心肌炎诊断的原始标准与2018年路易斯湖标准的比较：一个验证队列的结果
Radiol Cardiothorac Imaging. 2019 Jul 25;1(3):e190010. doi: 10.1148/ryct.2019190010. eCollection 2019 Aug.
5
COVID-19 and myocarditis: a systematic review and overview of current challenges.COVID-19 与心肌炎：系统综述及当前挑战概述。
Heart Fail Rev. 2022 Jan;27(1):251-261. doi: 10.1007/s10741-021-10087-9. Epub 2021 Mar 24.
6
Suspected myocarditis in patients with COVID-19: A multicenter case series.新型冠状病毒肺炎患者疑似心肌炎：一项多中心病例系列研究。
Medicine (Baltimore). 2021 Feb 26;100(8):e24552. doi: 10.1097/MD.0000000000024552.
Zotero 插件