Nickel J C, Olson M E, Costerton J W
Urology. 1987 May;29(5):501-3. doi: 10.1016/0090-4295(87)90037-9.
An animal model was developed to measure objectively the in vivo intrinsic coefficient of kinetic friction (COFk) of various catheter materials. Uncoated red rubber catheters had the highest COFk of the three materials tested. The Biocath catheter exhibited less COFk when compared with the standard silicone catheter. Although the etiology of urethral strictures is multifactorial, better biocompatibility as measured by in vivo COFk may be an important factor in the inevitable urethral trauma and irritation associated with indwelling catheterization and possibly with postcatheterization urethral stricture formation.
开发了一种动物模型，以客观测量各种导管材料的体内固有动摩擦系数（COFk）。在测试的三种材料中，未涂层的红色橡胶导管的COFk最高。与标准硅胶导管相比，Biocath导管的COFk更低。尽管尿道狭窄的病因是多因素的，但通过体内COFk测量的更好的生物相容性可能是与留置导尿相关的不可避免的尿道创伤和刺激以及可能与导尿后尿道狭窄形成相关的一个重要因素。
