Abdelsalam E B
Vet Hum Toxicol. 1987 Apr;29(2):146-8.
Cholinesterase (ChE) activity was measured in whole blood, plasma and certain tissues of goats experimentally poisoned with certain organophosphates, organochlorines, heavy metals and anthelmintic drugs. The enzyme activity was only inhibited by the organophosphorus compounds and not by any of the other substances used. The greatest inhibition occurred in the brain, although the blood ChE activity was concurrently inhibited in a similar degree.
在实验中用某些有机磷化合物、有机氯化合物、重金属和驱虫药使山羊中毒,然后测定了山羊全血、血浆和某些组织中的胆碱酯酶(ChE)活性。酶活性仅受到有机磷化合物的抑制,而未受到所使用的任何其他物质的抑制。尽管血液中的ChE活性同时受到了相似程度的抑制,但大脑中的抑制作用最为显著。