Subramanian Kumaran, Balaraman Deivasigamani, Kaliyaperumal Kumaravel, Devi Rajeswari V, Balakrishnan K, Ronald Ross P, Perumal Elumalai, Sampath Renuga Pugazhvendan, Panangal Mani, Swarnalatha Y, Velmurugan S
Centre for Drug Discovery and Development, Sathyabama Institute of Science and Technology, Chennai, Tamil Nadu 600119, India.
CAS in Marine Biology, Annamalai University, Cuddalore, Tamil Nadu, India.
Bioinorg Chem Appl. 2022 Jun 20;2022:7975873. doi: 10.1155/2022/7975873. eCollection 2022.
Hydrogel refers to a three-dimensional cross-linked polymeric network made of synthetic or natural polymers that can hold water in its porous structure. The inclusion of hydrophilic groups in the polymer chains, such as amino, carboxyl, and hydroxyl groups, contributes to the hydrogel's water-holding ability. At physiological temperature and pH, these polymeric materials do not dissolve in water, but they do swell significantly in aqueous media. Hydrogel can be manufactured out of almost any water-soluble polymer, and it comes in a variety of chemical compositions and bulk physical properties. Hydrogel can also be made in a variety of ways. Hydrogel comes in a variety of physical shapes, including slabs, microparticles, nanoparticles, coatings, and films. Due to its ease of manufacture and self-application in clinical and fundamental applications, hydrogel has been widely exploited as a drug carrier. Contact lenses, artificial corneas, wound dressing, suture coating, catheters, and electrode sensors are some of the biomedical applications of hydrogels. The pigment color changes were observed from colorless to pale pink followed by dark reddish-pink. Anthocyanin was produced in large quantities and tested using a UV-visible spectrophotometer. At 450-550 nm, the largest peak (absorbance) was detected, indicating the presence of anthocyanin. The FTIR analysis of this study shows the different stretches of bonds at different peaks: 2918.309 (-C-H alkane stretch), 2812.12 (-C-H aldehyde weak intensity), 192320.37/cm (C-O bend), 21915.50, 2029.08/cm (-C=C arene group), 1906.94/cm (=C-H aromatics), 1797.78/cm (=C-H), 1707.94 (-C=O ketene), 1579.70, 1382.96 (C-H alkane strong bend), 889.18/cm (C-H aromatics plane bend), and 412.77/cm (-C-CI strong bond). The spectra of the PVA/chitosan film depict the peak's formation: 1571.88, 1529.55, 1500.62/cm (C-H alkene strong bend), 1492.90, 1483.26, 1467.83/cm (C-H alkene strong bond), 670.48, 443.63, 412.77/cm (-O-H carboxylic acids with great intensity), 1708.93 (-C=O ketone), and 1656.0/cm (alkenyl C=C stretch strong bond).
水凝胶是指由合成或天然聚合物制成的三维交联聚合物网络，其多孔结构能够容纳水分。聚合物链中包含的亲水基团，如氨基、羧基和羟基，有助于水凝胶的保水能力。在生理温度和pH值下，这些聚合材料不溶于水，但它们在水性介质中会显著膨胀。几乎任何水溶性聚合物都可以制成水凝胶，它具有多种化学成分和整体物理性质。水凝胶也可以通过多种方式制备。水凝胶有多种物理形状，包括平板、微粒、纳米颗粒、涂层和薄膜。由于其易于制造且在临床和基础应用中可自行应用，水凝胶已被广泛用作药物载体。隐形眼镜、人工角膜、伤口敷料、缝线涂层、导管和电极传感器是水凝胶的一些生物医学应用。观察到色素颜色从无色变为浅粉色，然后变为深红色粉色。大量产生了花青素，并使用紫外可见分光光度计进行了测试。在450 - 550nm处检测到最大峰（吸光度），表明存在花青素。本研究的傅里叶变换红外光谱（FTIR）分析显示了不同峰处键的不同伸缩：2918.309（-C-H烷烃伸缩）、2812.12（-C-H醛弱强度）、192320.37/cm（C-O弯曲）、21915.50、2029.08/cm（-C=C芳烃基团）、1906.94/cm（=C-H芳烃）、1797.78/cm（=C-H）、1707.94（-C=O乙烯酮）、1579.70、1382.96（C-H烷烃强弯曲）、889.18/cm（C-H芳烃平面弯曲）和412.77/cm（-C-CI强键）。聚乙烯醇/壳聚糖膜的光谱描绘了峰的形成：1571.88、1529.55、1500.62/cm（C-H烯烃强弯曲）、1492.90、1483.26、1467.83/cm（C-H烯烃强键）、670.48, 443.63, 412.77/cm（-O-H羧酸高强度）、1708.93（-C=O酮）和1656.0/cm（烯基C=C伸缩强键）。
