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水凝胶系统在肿瘤治疗中的应用研究进展。

Research progress in the application of hydrogel system in tumor treatment.

机构信息

Department of Clinical Pharmacy, School of Pharmacy, Zunyi Medical University, Zunyi, China.

The Key Laboratory of Clinical Pharmacy in Zunyi City, Zunyi, China.

出版信息

Drug Deliv. 2020 Dec;27(1):460-468. doi: 10.1080/10717544.2020.1739171.

DOI:10.1080/10717544.2020.1739171
PMID:32166987
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7144265/
Abstract

The hydrogel drug delivery system is a hot research topic in recent years. Combining both properties of hydrogel and solution, hydrogels can provide many advantages for drug delivery application, including easy application, high local drug concentration, prolonged drug retention time, reduced drug dose , good biocompatibility and improved patient compliance, thus has potential in tumor treatment. In this paper, the related literature reports in recent years were reviewed to summarize and discuss the research progress and development prospects in the application of hydrogels in tumor treatment.

摘要

水凝胶药物输送系统是近年来的热门研究课题。水凝胶结合了水凝胶和溶液的特性,可为药物输送应用提供许多优势,包括易于应用、局部药物浓度高、药物滞留时间延长、药物剂量减少、良好的生物相容性和提高患者顺应性,因此在肿瘤治疗方面具有潜力。本文综述了近年来的相关文献,总结和讨论了水凝胶在肿瘤治疗中的应用研究进展和发展前景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef0c/7144265/fae2538b1baf/IDRD_A_1739171_F0001_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef0c/7144265/fae2538b1baf/IDRD_A_1739171_F0001_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef0c/7144265/fae2538b1baf/IDRD_A_1739171_F0001_C.jpg

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Carbohydr Polym. 2020 Mar 1;231:115745. doi: 10.1016/j.carbpol.2019.115745. Epub 2019 Dec 17.
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Graphene quantum dot cross-linked carboxymethyl cellulose nanocomposite hydrogel for pH-sensitive oral anticancer drug delivery with potential bioimaging properties.
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