心脏形态学与功能影像的相关性：心肌灌注单光子发射计算机断层扫描与CT血管造影的融合
Correlation of Morphological and Functional Cardiac Images: Fusion of Myocardial Perfusion SPECT and CT Angiography.
作者信息
Şan Hüseyin, Karaçalıoğlu Alper Özgür, Bozlar Uğur, İnce Semra, Alagöz Engin, Emer Mustafa Özdeş, Taşar Mustafa, Arslan Nuri
机构信息
University of Health Sciences Turkey, Ankara City Hospital, Clinic of Nuclear Medicine, Ankara, Turkey.
University of Health Sciences Turkey, Gülhane Training and Research Hospital, Clinic of Nuclear Medicine, Ankara, Turkey.
出版信息
Mol Imaging Radionucl Ther. 2022 Jun 27;31(2):89-95. doi: 10.4274/mirt.galenos.2022.00377.
OBJECTIVES
The current study evaluates the value of cardiac hybrid imaging (CHI), performed by the fusion of functional and anatomic cardiac images, in the detection of hemodynamically significant coronary stenosis in cases with multiple coronary stenosis.
METHODS
A total of 36 patients (10 female, 26 male) in whom ischemia or infarction was detected on gated myocardial perfusion single photon emission computed tomography (gMPS) and multiple coronary stenosis were concomitantly detected on coronary computed tomography angiography (CCTA) and undergone invasive coronary angiography (ICA) was included in this study. Statistical analyses were performed using SPSS 22 Windows software. McNemar test was applied to show concordance between coronary CT angiography, ICA and CHI in the detection of anatomically or hemodynamically significant stenosis in three major coronary arteries. Comparison results of coronary arteries responsible for perfusion defects on CHI and gMPS are presented as percentages (%).
RESULTS
There was total accordance between coronary arteries leading to perfusion defects detected by gMPS and CHI in 50% of patients. It was observed a partial accordance in 36.1% of the patients. Additionally, it was also detected perfusion defects originated from side branches in 25% of the patients. Between results of CCTA and ICA, no statistically significant difference was noted in the detection of anatomically significant stenoses in the left main coronary artery, left anterior descending artery (LAD), left circumflex artery (LCx) and right coronary artery (RCA) (p=1.000, 0.070, 0.549, and 1.000, respectively). In addition, no statistically significant difference was found in the detection of anatomically and hemodynamically significant stenoses in LAD, LCx and RCA by CCTA and CHI (p=0.344, 0.629, and 0.219, respectively). No statistically significant difference was observed in the detection of anatomically and hemodynamically significant stenoses in LAD, LCx and RCA by ICA and CHI (p=0.804, 1.000, and 0.344, respectively).
CONCLUSION
It is possible to detect hemodynamically significant coronary stenosis directly by CHI modality in patients with multiple coronary stenosis, wide perfusion defects.
目的
本研究评估通过融合心脏功能和解剖图像进行的心脏混合成像（CHI）在检测多支冠状动脉狭窄病例中血流动力学显著冠状动脉狭窄方面的价值。
方法
本研究纳入了36例患者（10例女性，26例男性），这些患者在门控心肌灌注单光子发射计算机断层扫描（gMPS）上检测到缺血或梗死，同时在冠状动脉计算机断层扫描血管造影（CCTA）上检测到多支冠状动脉狭窄并接受了有创冠状动脉造影（ICA）。使用SPSS 22 Windows软件进行统计分析。应用McNemar检验以显示冠状动脉CT血管造影、ICA和CHI在检测三大冠状动脉中解剖学或血流动力学显著狭窄方面的一致性。CHI和gMPS上导致灌注缺损的冠状动脉的比较结果以百分比（%）表示。
结果
50%的患者中，gMPS和CHI检测到的导致灌注缺损的冠状动脉完全一致。36.1%的患者观察到部分一致。此外，还在25%的患者中检测到源自侧支的灌注缺损。在CCTA和ICA的结果之间，在检测左主干冠状动脉、左前降支动脉（LAD）、左旋支动脉（LCx）和右冠状动脉（RCA）的解剖学显著狭窄方面未观察到统计学显著差异（p分别为1.000、0.070、0.549和1.000）。此外，CCTA和CHI在检测LAD、LCx和RCA的解剖学和血流动力学显著狭窄方面未发现统计学显著差异（p分别为0.344、0.629和0.219）。ICA和CHI在检测LAD、LCx和RCA的解剖学和血流动力学显著狭窄方面未观察到统计学显著差异（p分别为0.804、1.000和0.344）。
结论
对于多支冠状动脉狭窄、广泛灌注缺损的患者，通过CHI模式可以直接检测出血流动力学显著的冠状动脉狭窄。
Zotero 插件