Corfu General Hospital, Corfu, GR.
Methodist Debakey Cardiovasc J. 2022 Mar 14;18(2):94-105. doi: 10.14797/mdcvj.1068. eCollection 2022.
Sarcoidosis is a heterogeneous disease with various treatment indications. Although it affects mainly the lungs, sarcoidosis can affect every organ, especially when the disease course is chronic and protracted. Regular patient follow-up is recommended for early recognition of active, ongoing organ-specific granulomatous inflammation to avoid progression to irreversible fibrosis. In this review, we elaborate on treatment indications and various anti-sarcoidosis regimens proven useful in clinical trials. We also review specialized treatment of specific disease manifestations, with a focus on cardiac sarcoidosis. We also report on treatment for special conditions such as fatigue and small fiber neuropathy. Treatment for sarcoidosis is an emerging landscape, with new data complementing the existing knowledge.
结节病是一种异质性疾病，具有多种治疗指征。虽然它主要影响肺部，但结节病可以影响每个器官，特别是当疾病过程是慢性和长期的。建议对患者进行定期随访，以便早期识别活跃的、持续存在的器官特异性肉芽肿性炎症，以避免进展为不可逆转的纤维化。在这篇综述中，我们详细阐述了临床试验中证明有用的治疗指征和各种抗结节病方案。我们还回顾了特定疾病表现的专门治疗，重点是心脏结节病。我们还报告了特殊情况的治疗，如疲劳和小纤维神经病。结节病的治疗是一个新兴的领域，新的数据补充了现有知识。
